Laboratory of Polymer Materials, Department of Chemical Engineering and Chemistry, Eindhoven University of Technology, Den Dolech 2, 5600MB, Eindhoven, The Netherlands.
Macromol Rapid Commun. 2014 Jan;35(1):71-6. doi: 10.1002/marc.201300750. Epub 2013 Nov 22.
The synthesis, characterization, and testing of a range of novel bio-inspired L-DOPA-derived poly(ester amide)s is presented, using a widely applicable, straightforward chemistry. A model system is used to study and establish the monomer and polymer synthetic protocols, and to provide a set of optimum reaction conditions. It is further shown that fully biobased L-DOPA-containing adhesive tapes can be fabricated, which are positively evaluated in terms of their adhesive properties. The newly developed synthetic protocol constitutes a versatile platform for accessing and tailoring a plethora of relevant structures, including a variety of potentially biocompatible poly(ethylene glycol)-based materials.
本文提出了一系列新型生物启发的 L-DOPA 衍生聚酯酰胺的合成、表征和测试，采用了广泛适用、简单直接的化学方法。使用模型体系来研究和建立单体和聚合物的合成方案，并提供一套最佳的反应条件。进一步表明，可以制备出完全基于生物的含 L-DOPA 的胶带，并且从其粘性性能方面进行了积极的评价。新开发的合成方案构成了一种通用的平台，可以获得和调整大量相关结构，包括各种潜在的生物相容性聚乙二醇基材料。
