老年埃及人踝臂指数与冠状动脉疾病严重程度的相关性

Correlation between ankle brachial index and coronary artery disease severity in elderly Egyptians.

作者信息

Amer Moatasem S, Tawfik Heba Mohamed, Elmoteleb Ayman M Abd, Maamoun Manar M A

机构信息

Geriatric Medicine & Gerontology Department, Ain Shams University, Cairo, Egypt.

Geriatric Medicine & Gerontology Department, Ain Shams University, Cairo, Egypt

出版信息

Angiology. 2014 Nov;65(10):891-5. doi: 10.1177/0003319713510594. Epub 2013 Nov 21.

DOI:10.1177/0003319713510594

PMID:24265249

Abstract

We investigated the association between ankle brachial index (ABI) and coronary heart disease (CHD) severity in elderly Egyptians using different measures. We conducted a case-control study from November 2010 to June 2012 including 200 male and female patients with ischemia≥60 years who were divided into 100 cases and 100 controls according to ABI and redivided according to age. They underwent coronary angiography followed by ABI measurement using a hand-held Doppler. The CHD severity was estimated using the SYNTAX and Jeopardy scores and number of diseased vessels, which increased significantly in patients with peripheral artery disease (P<.001) for all. All 3 measures had strong negative correlation with ABI (P≤.001 for Jeopardy, <.001 for SYNTAX scores, and .004 for number of diseased vessels) and were correlated with each other. We concluded that ABI can reflect CHD severity in elderly Egyptians.

摘要

我们采用不同测量方法，研究了老年埃及人踝臂指数（ABI）与冠心病（CHD）严重程度之间的关联。我们在2010年11月至2012年6月期间开展了一项病例对照研究，纳入了200名年龄≥60岁的男性和女性缺血性患者，这些患者根据ABI分为100例病例组和100例对照组，并根据年龄再次分组。他们接受了冠状动脉造影，随后使用手持式多普勒仪测量ABI。使用SYNTAX和危险评分以及病变血管数量评估冠心病严重程度，在外周动脉疾病患者中，所有这些指标均显著升高（P<0.001）。所有这3项指标均与ABI呈强负相关（危险评分为P≤0.001，SYNTAX评分为<0.001，病变血管数量为0.004），且彼此相关。我们得出结论，ABI能够反映老年埃及人冠心病的严重程度。