Dion J E, Rankin R N, Viñuela F, Fox A J, Wallace A C, Mervart M
Radiology. 1986 Sep;160(3):717-21. doi: 10.1148/radiology.160.3.2426727.
The radiologic and pathologic effects of canine renal embolization with dextran microspheres of two size ranges (40-150 micron and 100-300 micron) were studied 30 minutes and 1, 2, 4, and 6 weeks after embolization. Dramatic occlusions occurred with very small quantities of these particles, which reached more distally and were suspended and embolized more easily than other solid embolic agents. Because of these qualities, however, they should be used with more caution. They can be injected through 2-F catheters, calibrated-leak balloons, and open-ended guide wires. Embolization with dextran microspheres was also used for epistaxis, meningioma, dural arteriovenous malformation, renal tumors, bone metastasis, multiple myeloma, or peripheral angioma in ten patients. The technique was safe and effective, but special attention should be directed to proper dilution and gentle embolization with careful monitoring to avoid excessive embolization or reflux.
研究了两种粒径范围（40 - 150微米和100 - 300微米）的葡聚糖微球对犬肾栓塞的放射学和病理学影响，观察时间为栓塞后30分钟以及1、2、4和6周。极少量的这些颗粒就能造成显著的阻塞，它们比其他固体栓塞剂能到达更远端的部位，并且更容易悬浮和栓塞。然而，由于这些特性，使用时应更加谨慎。它们可以通过2F导管、校准漏气球囊和开口导丝进行注射。十名患者还使用葡聚糖微球栓塞治疗鼻出血、脑膜瘤、硬脑膜动静脉畸形、肾肿瘤、骨转移、多发性骨髓瘤或周围血管瘤。该技术安全有效，但应特别注意适当稀释并轻柔栓塞，同时仔细监测以避免过度栓塞或反流。
