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量化梯度压力弹力袜增强静脉排空的程度。

Quantifying the degree graduated elastic compression stockings enhance venous emptying.

机构信息

Josef Pflug Vascular Laboratory, Ealing Hospital, Southall, UK; Imperial College, London, UK.

Josef Pflug Vascular Laboratory, Ealing Hospital, Southall, UK; Imperial College, London, UK.

出版信息

Eur J Vasc Endovasc Surg. 2014 Jan;47(1):75-80. doi: 10.1016/j.ejvs.2013.10.020. Epub 2013 Oct 30.

Abstract

OBJECTIVES

Graduated elastic compression (GEC) stockings reduce reflux and venous volume but their performance on augmenting venous return is unproven. The aim of this study was to quantify the ability of stockings to increase venous outflow from the leg.

DESIGN

A prospective study comparing venous emptying without compression, versus class 1 (18-21 mmHg) and class 2 (23-32 mmHg) compression, using air-plethysmography (APG).

METHODS

The right legs of 20 healthy subjects were studied supine. A 12-cm thigh-cuff was inflated in 10 mmHg steps from 0 to 80 mmHg while the corresponding increase in calf volume was recorded using the APG sensor calf-cuff. At the 80 mmHg plateau, the thigh-cuff was released suddenly to measure the unrestricted venous emptying. Venous return was assessed by: (a) identifying the incremental thigh-cuff pressure causing the maximal incremental increase in calf volume (IPMIV); (b) measuring the percentage reduction in calf volume in 1 second following thigh-cuff release - outflow fraction (OF); (c) time to empty 90% of the venous volume - venous emptying time (VET90).

RESULTS

Median and inter-quartile range (IQR) baseline values of IPMIV, OF, and VET90 without compression were 20 mmHg (range: 20-30 mmHg), 44% (39-50%) and 13 seconds (8.8-15.9 seconds), respectively. These improved significantly with all stockings. The application of any stocking raised the median IPMIV by 30 mmHg. The change from a class 2 stocking compared with no stocking versus the change from a class 1 stocking to no stocking had a more pronounced effect (p < .005). After sudden thigh-cuff deflation, the venous emptying was 41-45% greater and 9-10 seconds faster with all stockings (p < .005).

CONCLUSIONS

This is the first study to quantify the venous return of below-knee GEC stockings. Assessments of stockings in augmenting venous return may be of use as a way of optimising compression for individual patients unresponsive to standard conservative treatment.

摘要

目的

梯度压力弹力袜(GEC)可减少反流和静脉容积,但它们增加静脉回流的效果尚未得到证实。本研究旨在定量评估袜子增加腿部静脉流出的能力。

设计

前瞻性研究,使用空气容积描记法(APG)比较无压缩、1 级(18-21mmHg)和 2 级(23-32mmHg)压缩时的静脉排空情况。

方法

20 名健康受试者仰卧位,12cm 大腿袖带以 10mmHg 的步长从 0 充气至 80mmHg,同时使用 APG 传感器袖带记录小腿容积的相应增加。在 80mmHg 平台期,突然释放大腿袖带以测量不受限制的静脉排空。通过以下方法评估静脉回流:(a)确定导致小腿容积最大增量的增量大腿袖带压力(IPMIV);(b)测量大腿袖带释放后 1 秒内小腿容积的百分比减少量-流出分数(OF);(c)排空 90%静脉容积所需的时间-静脉排空时间(VET90)。

结果

无压缩时,IPMIV、OF 和 VET90 的中位数和四分位数范围(IQR)基线值分别为 20mmHg(范围:20-30mmHg)、44%(39-50%)和 13 秒(8.8-15.9 秒)。所有袜子均显著改善。任何袜子的应用都会使中位数 IPMIV 增加 30mmHg。与无袜子相比,2 级袜子的变化比 1 级袜子的变化更明显(p<0.005)。大腿袖带突然放气后,所有袜子的静脉排空量增加 41-45%,速度加快 9-10 秒(p<0.005)。

结论

这是首次定量评估膝下 GEC 袜子的静脉回流。评估袜子增加静脉回流的能力可能有助于优化对标准保守治疗无反应的个体患者的压缩。

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