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一项关于丁丙诺啡用于阿片类药物成瘾治疗的采用情况的定性研究。

A qualitative study of the adoption of buprenorphine for opioid addiction treatment.

作者信息

Green Carla A, McCarty Dennis, Mertens Jennifer, Lynch Frances L, Hilde Anadam, Firemark Alison, Weisner Constance M, Pating David, Anderson Bradley M

机构信息

Kaiser Permanente Center for Health Research; 3800N. Interstate Avenue, Portland, OR 97227-1110.

Dept. of Public Health & Preventive Medicine, Oregon Health & Science University; 3181S.W. Sam Jackson Hill Road, CB 669, Portland, OR 97239.

出版信息

J Subst Abuse Treat. 2014 Mar;46(3):390-401. doi: 10.1016/j.jsat.2013.09.002. Epub 2013 Oct 23.

Abstract

Qualified physicians may prescribe buprenorphine to treat opioid dependence, but medication use remains controversial. We examined adoption of buprenorphine in two not-for-profit integrated health plans, over time, completing 101 semi-structured interviews with clinicians and clinician-administrators from primary and specialty care. Transcripts were reviewed, coded, and analyzed. A strong leader championing the new treatment was critical for adoption in both health plans. Once clinicians began using buprenorphine, patients' and other clinicians' experiences affected decisions more than did the champion. With experience, protocols developed to manage unsuccessful patients and changed to support maintenance rather than detoxification. Diffusion outside addiction and mental health settings was nonexistent; primary care clinicians cited scope-of-practice issues and referred patients to specialty care. With greater diffusion came questions about long-term use and safety. Recognizing how implementation processes develop may suggest where, when, and how to best expend resources to increase adoption of such treatments.

摘要

合格的医生可以开丁丙诺啡来治疗阿片类药物依赖,但药物使用仍然存在争议。我们研究了两个非营利性综合健康计划中丁丙诺啡随时间推移的采用情况,对来自初级保健和专科护理的临床医生及临床医生管理人员进行了101次半结构化访谈。对访谈记录进行了审查、编码和分析。一位大力支持新疗法的强有力领导者对于两个健康计划中该疗法的采用至关重要。一旦临床医生开始使用丁丙诺啡,患者和其他临床医生的经验对决策的影响超过了倡导者。随着经验的积累,制定了管理治疗失败患者的方案,并进行了调整以支持维持治疗而非戒毒。在成瘾和心理健康环境之外不存在传播;初级保健临床医生提到了执业范围问题,并将患者转诊至专科护理。随着传播范围的扩大,出现了关于长期使用和安全性的问题。认识到实施过程如何发展可能会提示在哪里、何时以及如何最好地投入资源以增加此类治疗方法的采用。

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