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ST段抬高型心肌梗死直接经皮冠状动脉介入治疗的操作差异:一项基于美国心血管造影和介入学会的美国介入心脏病学家调查研究。

Procedural variation in the performance of primary percutaneous coronary intervention for ST-elevation myocardial infarction: a SCAI-based survey study of US interventional cardiologists.

作者信息

Chiang Austin, Gada Hemal, Kodali Susheel K, Lee Michael S, Jeremias Allen, Pinto Duane S, Bangalore Sripal, Yeh Robert W, Henry Timothy D, Lopez-Cruz Georgina, Mehran Roxana, Kirtane Ajay J

机构信息

Columbia University Medical Center/New York Presbyterian Hospital and The Cardiovascular Research Foundation, New York.

出版信息

Catheter Cardiovasc Interv. 2014 Apr 1;83(5):721-6. doi: 10.1002/ccd.25276. Epub 2013 Nov 25.

Abstract

BACKGROUND

Great strides have been made in improving outcomes for patients with ST-elevation myocardial infarction (STEMI), predominately through initiatives focusing upon improving clinical processes "upstream" of percutaneous coronary intervention (PCI). The actual step-by-step mechanics of diagnostic angiography during STEMI and other aspects of the PCI procedure itself have received relatively little attention.

OBJECTIVES AND METHODS

We hypothesized that there would be significant variation in how primary PCI for STEMI is performed in the United States. In order to better understand current US practice, an electronic survey consisting of seven focused questions was forwarded to 2,910 US interventional cardiologists who were members of the Society for Cardiovascular Angiography and Interventions (SCAI).

RESULTS

Three hundred sixty-two responses were received (12.4%). Among respondents, the femoral artery was the preferred access site in 83% (vs. 17% radial). The use of a diagnostic catheter to visualize the non-culprit artery prior to using a guiding catheter for the culprit artery was the preferred approach for 58% of respondents, and an additional 23% preferred complete angiography with diagnostic catheters prior to guide insertion. However, a significant minority (19%) preferred starting directly with a guide catheter for the culprit artery and performing PCI prior to contralateral non-culprit artery visualization. Only 9% reported performing routine left ventriculography prior to PCI, with the majority (66%) choosing to perform ventriculography during/after PCI, and 25% reporting rare or no use of left ventriculography. Fewer than half of respondents (49%) reported routine aspiration thrombectomy use, despite a Class IIa ACC/AHA guidelines recommendation.

CONCLUSIONS

There is significant variability in the self-reported mechanics of primary PCI by US interventional cardiologists. Some of this variability (e.g., sequence of catheters, and performance of left ventriculography prior to reperfusion) is not addressed by current guidelines/consensus documents, and may have clinical implications, reflecting the balance between the desire for timely reperfusion versus a more complete assessment of patient risk.

摘要

背景

在改善ST段抬高型心肌梗死(STEMI)患者的治疗结果方面已经取得了巨大进展,主要是通过关注改善经皮冠状动脉介入治疗(PCI)“上游”临床流程的举措。STEMI诊断性血管造影的实际逐步操作机制以及PCI手术本身的其他方面受到的关注相对较少。

目的和方法

我们假设在美国,STEMI的直接PCI操作方式会存在显著差异。为了更好地了解美国目前的做法,向2910名美国心血管造影和介入学会(SCAI)成员的介入心脏病专家发送了一份包含七个重点问题的电子调查问卷。

结果

共收到362份回复(12.4%)。在受访者中,83%的人首选股动脉作为穿刺部位(桡动脉为17%)。58%的受访者首选在使用引导导管处理罪犯血管之前,先用诊断导管观察非罪犯血管,另有23%的受访者更喜欢在插入引导导管之前先用诊断导管进行完整的血管造影。然而,相当少数(19%)的人更喜欢直接用引导导管处理罪犯血管,并在对侧非罪犯血管显影之前进行PCI。只有9%的人报告在PCI之前常规进行左心室造影,大多数(66%)选择在PCI期间/之后进行心室造影,25%的人报告很少或不使用左心室造影。尽管美国心脏病学会/美国心脏协会(ACC/AHA)指南有IIa类推荐,但不到一半的受访者(49%)报告常规使用血栓抽吸术。

结论

美国介入心脏病专家自我报告的直接PCI操作机制存在显著差异。其中一些差异(例如导管使用顺序以及再灌注前的左心室造影操作)未被当前指南/共识文件涉及,可能具有临床意义,反映了及时再灌注需求与更全面评估患者风险之间的平衡。

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