Pettifer Annie, Grant Sarah
Coventry University, Priory Street, Coventry CV1 SFU, England.
Int J Palliat Nurs. 2013 Jul;19(7):327-31. doi: 10.12968/ijpn.2013.19.7.327.
Hypercalcaemia is common in patients with advanced cancer. If detected, it usually responds to palliative treatment and patients' distressing symptoms will improve markedly. However, if left untreated hypercalcaemia is potentially fatal. It can be difficult to detect as its symptoms can also be attributed to other common aspects of advanced malignancy. It is therefore essential that nurses are aware of the underlying physiology and can identify which patients are at risk of becoming hypercalcaemic. Hypercalcaemia often recurs and can become increasingly difficult to treat. Such refractory hypercalcaemia requires sensitive and considered management with advance care planning, particularly as difficult treatment dilemmas may arise if and when malignancy advances.
高钙血症在晚期癌症患者中很常见。如果被检测到,通常对姑息治疗有反应,患者的痛苦症状会明显改善。然而,如果不进行治疗,高钙血症可能会致命。由于其症状也可能归因于晚期恶性肿瘤的其他常见方面,因此可能难以检测到。因此,护士必须了解潜在的生理机制,并能够识别哪些患者有发生高钙血症的风险。高钙血症常复发,且治疗可能会越来越困难。这种难治性高钙血症需要通过预先护理计划进行敏感且周全的管理,尤其是当恶性肿瘤进展时可能会出现棘手的治疗困境。