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啮齿类动物的甲状腺疾病。

Thyroid diseases in rodent species.

作者信息

Thorson Lindsay

机构信息

Central Animal Hospital, 317 Ardsley Road, Scarsdale, NY 10583, USA.

出版信息

Vet Clin North Am Exot Anim Pract. 2014 Jan;17(1):51-67. doi: 10.1016/j.cvex.2013.09.002.

Abstract

There are an abundance of studies of thyroid disease in rodents in a laboratory setting; however, research is limited in pet rodent populations. Validated reference intervals for thyroid testing are scarce, making interpretation of blood work difficult. Hyperthyroidism and hypothyroidism have been reported in multiple rodent species, with the most data available for guinea pigs. Thyroid neoplasia has been reported in the most common rodent species, although often as an incidental finding at necropsy. Further research is needed to determine frequencies of disease, methods of diagnosing, and treatment options with the best efficacy.

摘要

在实验室环境中,对啮齿动物甲状腺疾病的研究有很多;然而,对宠物啮齿动物群体的研究却很有限。经过验证的甲状腺检测参考区间很少,这使得血液检测结果的解读变得困难。多种啮齿动物物种都有甲状腺功能亢进和甲状腺功能减退的报道,其中豚鼠的相关数据最多。在最常见的啮齿动物物种中也有甲状腺肿瘤的报道,不过通常是在尸检时偶然发现的。需要进一步研究来确定疾病的发生率、诊断方法以及疗效最佳的治疗方案。

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