肌萎缩侧索硬化症的管理
Management of amyotrophic lateral sclerosis.
作者信息
Bali Taha, Miller Timothy M
机构信息
Neuromuscular Disease Division, Washington University School of Medicine, St. Louis, USA.
出版信息
Mo Med. 2013 Sep-Oct;110(5):417-21.
Abstract
Motor Neuron Diseases (MNDs) are neurological disorders characterized by the selective and progressive degeneration of motor neurons. Amyotrophic Lateral Sclerosis (ALS), commonly known as Lou Gehrig's disease, is the most common. ALS causes diffuse muscle weakness and death secondary to respiratory failure. The diagnosis is made clinically, supported by electrodiagnostic testing. Although medications are limited, careful attention to breathing, nutrition, and patient mobility can have a major, positive impact on the course of the disease.
摘要
运动神经元病（MNDs）是一类以运动神经元的选择性和进行性退变为特征的神经疾病。肌萎缩侧索硬化症（ALS），通常被称为卢伽雷氏病，是最常见的一种。ALS会导致广泛的肌肉无力，并因呼吸衰竭而致死。诊断主要依靠临床症状，并通过电诊断测试来辅助。尽管治疗药物有限，但对呼吸、营养和患者活动能力的密切关注可对疾病进程产生重大的积极影响。
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