Via Department of Civil and Environmental Engineering, Virginia Polytechnic Institute and State University , Blacksburg, Virginia 24061, United States.
Environ Sci Technol. 2014;48(1):5-14. doi: 10.1021/es403883p. Epub 2013 Dec 11.
Global initiatives are underway to advance the sustainability of urban water infrastructure through measures such as water reuse. However, there are growing concerns that wastewater effluents are enriched in antibiotics, antibiotic resistant bacteria, and antibiotic resistance genes, and thus could serve as a contributing factor to growing rates of antibiotic resistance in human infections. Evidence for the role of the water environment as a source and pathway for the spread of antimicrobial resistance is examined and key knowledge gaps are identified with respect to implications for sustainable water systems. Efforts on the part of engineers along with investment in research in epidemiology, risk assessment, water treatment and water delivery could advance current and future sustainable water strategies and help avoid unintended consequences.
全球范围内正在采取各种措施，例如水再利用，来推动城市水基础设施的可持续性。然而，人们越来越担心废水中富含抗生素、抗药性细菌和抗生素抗性基因，因此可能成为人类感染中抗生素抗性不断增长的一个促成因素。本文研究了水环境作为抗生素耐药性传播的源头和途径的作用，并确定了与可持续水系统相关的主要知识空白。工程师的努力以及在流行病学、风险评估、水处理和供水方面的研究投资，可以推进当前和未来的可持续水战略，并有助于避免意想不到的后果。
