Watanabe Shin, Saito Naritatsu, Bao Bingyuan, Tokushige Akihiro, Watanabe Hiroki, Yamamoto Erika, Kawase Yoshiaki, Kimura Takeshi
Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
EuroIntervention. 2013 Nov;9(7):870-7. doi: 10.4244/EIJV9I7A141.
To assess when and how the microcatheter-facilitated reverse wire technique should be applied to cross the guidewire into side branches in coronary bifurcations.
Three interventional cardiologists with different levels of experience performed in vitro bench testing using an originally developed coronary bifurcation simulator which had six coronary bifurcations. The bifurcation angles were 90, 105, 120, 135, 150 and 165 degrees (°). Experiment 1 was conducted to assess in what coronary bifurcation the reverse wire technique is required. Antegrade guidewire advancement was conducted with two different guidewires: the spring coil guidewire SION blue and the polymer-jacket hydrophilic guidewire Fielder FC. Experiment 2 was conducted to determine what the optimal guidewire selection and the optimal guidewire shape for the reverse wire technique would be. Assessment of the guidewire crossability into the highly angulated side branch was performed, and then the balloon crossability was assessed. A total of four guidewire types were compared in experiment 2. In experiment 1, guidewire crossing was impossible by conventional antegrade wiring when the bifurcation angle became 150° or more. In experiment 2, guidewire crossing of more than 150° of bifurcation angle was achievable independent of the guidewire types and shape. Balloon deliverability was best when using a polymer-jacket hydrophilic guidewire with a round shape 3 cm from the guidewire tip.
Although the guidewire crossing into the side branch was impossible by conventional antegrade methods when the bifurcation angle became 150° or more, the guidewire crossing into such a highly angulated side branch was easily possible using the reverse wire technique. The optimal guidewire selection for the reverse wire technique is the polymer-jacket hydrophilic guidewire with a round shape 3 cm from the guidewire tip.
评估微导管辅助逆向导丝技术应在何时以及如何应用于使导丝穿过冠状动脉分叉处的侧支血管。
三位经验水平不同的介入心脏病专家使用最初开发的具有六个冠状动脉分叉的冠状动脉分叉模拟器进行了体外实验台测试。分叉角度分别为90°、105°、120°、135°、150°和165°。实验1旨在评估在何种冠状动脉分叉情况下需要逆向导丝技术。使用两种不同的导丝进行正向导丝推进:弹簧圈导丝SION blue和聚合物护套亲水导丝Fielder FC。实验2旨在确定逆向导丝技术的最佳导丝选择和最佳导丝形状。评估导丝进入高度成角侧支血管的可通过性,然后评估球囊的可通过性。在实验2中比较了总共四种导丝类型。在实验1中,当分叉角度达到150°或更大时,通过传统正向布线无法实现导丝穿过。在实验2中,无论导丝类型和形状如何,均可实现分叉角度超过150°的导丝穿过。当使用距离导丝尖端3 cm处呈圆形的聚合物护套亲水导丝时,球囊输送效果最佳。
尽管当分叉角度达到150°或更大时,通过传统正向方法无法使导丝穿过侧支血管,但使用逆向导丝技术可轻松使导丝穿过如此高度成角的侧支血管。逆向导丝技术的最佳导丝选择是距离导丝尖端3 cm处呈圆形的聚合物护套亲水导丝。