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复杂冠状动脉分叉病变反向导丝技术失败的预测因素

Predictors of failure in the reverse wire technique for complex coronary bifurcation lesions.

作者信息

Murasato Yoshinobu, Meno Kyohei, Omura Soichiro, Ura Yujiro, Mori Takahiro

出版信息

AsiaIntervention. 2025 Jul 30;11(2):e110-e118. doi: 10.4244/AIJ-D-24-00069. eCollection 2025 Jul.

Abstract

BACKGROUND

The reverse wire technique (RWT), with a guidewire shaped in a swan-neck configuration, is used to address challenging side branch (SB) wiring in complex coronary bifurcation lesions (CBLs). However, its success is not guaranteed.

AIMS

This study aimed to identify factors associated with RWT failure and to assess the feasibility of the balloon blocking technique (BBT) in the distal main vessel (MV) as an alternative.

METHODS

Thirty-two consecutive complex CBLs with difficult SB wiring were retrospectively analysed. Patients were divided into two groups: those with successful RWT (RWT-S, n=17) and those who underwent BBT, either after RWT failure or as a primary approach (RWT-F/BBT, n=15). Risk factors for RWT failure were examined.

RESULTS

The success rate of SB wiring with BBT was 80%. RTW-F/BBT was associated with less involvement of the left anterior descending artery (40% vs 71%), smaller-diameter MV stent implantation (2.8±0.5 mm vs 3.2±0.5 mm), wider bifurcation angle (BA) between the distal MV and middle SB (BA-β: 51.6±29.8° vs 36.4±18.6°), and smaller minimum lumen diameter (MLD) in the distal MV (1.72±0.68 mm vs 2.14±0.58 mm). SB calcification (33% vs 0%; p=0.01), severe bending in the distal MV (53% vs 12%; p=0.02) and severe bending in the SB (73% vs 24%; p=0.01) were more common in the RTW-F/BBT group. A receiver operating characteristic curve analysis showed that a combination of preprocedural BA-β >34.1°, distal MV MLD <1.77 mm, and SB calcification had good discrimination ability for predicting RWT failure (area under the curve 0.85, 95% confidence interval: 0.71-0.98).

CONCLUSIONS

RWT is challenging in complex CBLs with calcification, significant tortuosity, and small vessels. BBT offers a viable alternative in these cases.

摘要

背景

反向导丝技术(RWT)采用呈天鹅颈形态塑形的导丝,用于处理复杂冠状动脉分叉病变(CBL)中具有挑战性的边支(SB)布线。然而,其成功率并无保障。

目的

本研究旨在确定与RWT失败相关的因素,并评估球囊阻断技术(BBT)在远端主支血管(MV)中作为替代方法的可行性。

方法

对32例连续的具有困难SB布线的复杂CBL进行回顾性分析。患者分为两组:RWT成功组(RWT-S,n = 17)和在RWT失败后或作为主要方法接受BBT的患者(RWT-F/BBT,n = 15)。检查RWT失败的危险因素。

结果

BBT进行SB布线的成功率为80%。RWT-F/BBT与左前降支受累较少(40%对71%)、MV支架植入直径较小(2.8±0.5 mm对3.2±0.5 mm)、远端MV与中间SB之间的分叉角度(BA)更宽(BA-β:51.6±29.8°对36.4±18.6°)以及远端MV最小管腔直径(MLD)较小(1.72±0.68 mm对2.14±0.58 mm)相关。SB钙化(33%对0%;p = 0.01)、远端MV严重弯曲(53%对12%;p = 0.02)和SB严重弯曲(73%对24%;p = 0.01)在RWT-F/BBT组中更为常见。受试者工作特征曲线分析显示,术前BA-β>34.1°、远端MV MLD<1.77 mm和SB钙化的组合对预测RWT失败具有良好的鉴别能力(曲线下面积0.85,95%置信区间:0.71 - 0.98)。

结论

在伴有钙化、显著迂曲和小血管的复杂CBL中,RWT具有挑战性。在这些情况下,BBT提供了一种可行的替代方法。

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