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全主动脉弓修复联合开放三分支支架置入治疗急性A型主动脉夹层:122 例患者的经验。

Total arch repair with open triple-branched stent graft placement for acute type A aortic dissection: experience with 122 patients.

机构信息

Department of Cardiac Surgery, Union Hospital, Fujian Medical University, Fuzhou, Fujian, China.

Department of Cardiac Surgery, Union Hospital, Fujian Medical University, Fuzhou, Fujian, China.

出版信息

J Thorac Cardiovasc Surg. 2014 Aug;148(2):521-8. doi: 10.1016/j.jtcvs.2013.10.021. Epub 2013 Nov 23.

Abstract

OBJECTIVE

To summarize the clinical experiences and midterm follow-up results of total arch repair with open triple-branched stent graft placement for acute type A aortic dissection.

METHODS

From June 2008 to March 2013, 122 patients (95 men and 27 women; mean age, 50.9 ± 10.4 years) with acute type A aortic dissection underwent total arch repair with open placement of a triple-branched stent graft under hypothermic cardiopulmonary bypass and selective cerebral perfusion. During the follow-up period, enhanced computed tomography and echocardiography were performed at 3 months postoperatively and annually thereafter.

RESULTS

Placement of the triple-branched stent graft into the true lumen of the descending aorta, arch, and 3 arch vessels was technically successful in 121 patients. The cardiopulmonary bypass time was 186.50 ± 38.23 minutes, and the selective antegrade cerebral perfusion time was 31.97 ± 10.08 minutes. The in-hospital mortality was 4.93%. No permanent neurologic dysfunction or paraplegia was observed. Three patients were lost to follow-up. The mean follow-up period was 30.24 ± 12.35 months. After hospital discharge, 3 patients died. On the 3-month postoperative scans, complete thrombus formation around the triple-branched stent graft was observed in 89.38% of the patients. Endoleaks were detected in 12 patients; 8 patients refused any management for the endoleaks, but they maintained a good quality of life. The other 4 patients were successfully treated by additional surgery.

CONCLUSIONS

Total arch repair with open triple-branched stent graft placement is an effective technique with satisfactory early and midterm results. This technique could be an attractive alternative to conventional total arch replacement.

摘要

目的

总结急性 A 型主动脉夹层行全弓置换并开放植入三分支支架型人工血管的临床经验和中期随访结果。

方法

2008 年 6 月至 2013 年 3 月,122 例急性 A 型主动脉夹层患者(男 95 例,女 27 例;平均年龄 50.9±10.4 岁)在体外循环和选择性脑灌注下接受全弓置换并开放植入三分支支架型人工血管。随访期间,术后 3 个月及此后每年行增强 CT 和超声心动图检查。

结果

121 例患者成功将三分支支架型人工血管植入降主动脉、弓部和 3 个弓部血管真腔。体外循环时间为 186.50±38.23 分钟,选择性顺行脑灌注时间为 31.97±10.08 分钟。院内死亡率为 4.93%。无永久性神经功能障碍或截瘫。3 例患者失访。平均随访时间为 30.24±12.35 个月。出院后 3 例患者死亡。术后 3 个月扫描显示,89.38%的患者三分支支架型人工血管周围完全血栓形成。12 例患者发现内漏,8 例患者拒绝任何内漏处理,但生活质量良好。其余 4 例患者通过额外手术成功治疗。

结论

全弓置换并开放植入三分支支架型人工血管是一种有效的技术,具有满意的早期和中期结果。该技术可能成为传统全弓置换的一种有吸引力的替代方法。

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