Dipartimento di Chimica and IMC-CNR, Università La Sapienza, 00185 Roma, Italy.
Chem Commun (Camb). 2014 Jan 18;50(5):611-3. doi: 10.1039/c3cc47447j. Epub 2013 Nov 26.
The phenylurea moiety is a ubiquitous synthon in supramolecular chemistry. Here we report that the introduction of chlorine or bromine atoms in the ortho positions to the urea unit is a simple and very efficient way to improve its intermolecular hydrogen bond (HB) donor character. This effect was demonstrated in solution both in the context of self-association of bis-ureas and hydrogen bonding of mono-ureas to strong HB acceptors.
苯脲部分是超分子化学中无处不在的结构单元。在这里，我们报告说，在脲单元的邻位引入氯原子或溴原子是一种简单而非常有效的方法，可以提高其分子间氢键（HB）供体性质。这种效应在二脲自组装和单脲与强 HB 受体氢键的情况下，在溶液中都得到了证明。
