The Department of Epidemiology and Biostatistics, George Washington University School of Public Health and Health Services, Washington, DC, 20037, USA.
Cancers (Basel). 2010 Mar 3;2(1):143-52. doi: 10.3390/cancers2010143.
The case definition for inflammatory breast cancer (IBC) is controversial. The American Joint Committee on Cancer defines IBC as redness, warmth and edema involving at least half the breast. The SEER program relies on a pathologic finding of dermal lymphatic invasion and recently added those with clinical involvement of more than 3/4 of the breast. We established a registry to collect information and specimens from IBC patients to clarify the epidemiology and biology of these tumors. The goals of this report are to suggest improvements regarding case definitions and provide data on the variety of presentations relevant to early diagnosis.
炎性乳腺癌（IBC）的病例定义存在争议。美国癌症联合委员会将 IBC 定义为至少一半乳房出现红肿、发热和水肿。SEER 计划依赖于真皮淋巴管浸润的病理发现，并最近增加了那些临床累及超过 3/4 乳房的病例。我们建立了一个登记处，收集 IBC 患者的信息和标本，以阐明这些肿瘤的流行病学和生物学。本报告的目的是建议改进病例定义，并提供有关早期诊断相关各种表现的数据。
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