不可切除转移性黑色素瘤的系统性治疗。
Systemic therapy of non-resectable metastatic melanoma.
机构信息
Department of Dermatology, Venereology and Allergology, University Medical Center Mannheim, Ruprecht-Karl University of Heidelberg, Mannheim, Germany.
出版信息
Cancers (Basel). 2010 May 26;2(2):955-69. doi: 10.3390/cancers2020955.
Abstract
In advanced metastatic melanoma (non-resectable stage III/IV), the prognosis still remains poor, with median survival times between six and twelve months. Systemic therapeutic approaches for metastatic melanoma include chemotherapy, immunotherapy, immunochemotherapy, small molecules and targeted therapy. In this review, we will focus on the various treatment modalities as well as new agents used for targeted therapy.
摘要
在晚期转移性黑色素瘤（不可切除的 III/IV 期）中，预后仍然较差，中位生存时间为 6 至 12 个月。转移性黑色素瘤的系统治疗方法包括化疗、免疫疗法、免疫化疗、小分子药物和靶向治疗。在这篇综述中，我们将重点介绍各种治疗方式以及用于靶向治疗的新药物。
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