妊娠20至24周单胎和双胎妊娠的结局：一家围产期中心的十年经验
Outcome in single and twin pregnancies at 20 to 24 weeks gestation: ten years experience in one perinatal center.
作者信息
Louwen F, Antwerpen I, Ernst T, Reichenbach L, Reitter A, Herrmann E, Yuan J, Reinhard J
机构信息
Department of Obstetrics and Gynaecology, Johann Wolfgang Goethe-University, Frankfurt am Main, Faculty of Medicine, Frankfurt am Main, Germany.
出版信息
Clin Exp Obstet Gynecol. 2013;40(3):342-4.
OBJECTIVE
The aim of this investigation was to evaluate the outcome at 20 to 24 weeks gestation of twin and singleton extremely low birth weight infants.
STUDY DESIGN
The authors conducted a retrospective cohort study of live newborns at 20 to 24 weeks gestation admitted to one neonatal intensive care unit (NICU) from 2000 to 2009. Outcome mortality and predictors of outcome were evaluated. Results were compared for twin and singleton infants.
RESULTS
The cohort of infants consisted of 60 singleton infants and 17 twins. The results suggest an increased risk of death for twins when compared with singletons. A correlation between neonatal C-reactive protein (CRP) and bacterial culture positive results on admission to NICU might be a predictor of neonatal outcome.
CONCLUSION
In extremely low birth weight infants, twin delivery is associated with an independent increased risk of death. Both first- and second-born twins are at increased risk.
目的
本研究旨在评估孕20至24周的双胎及单胎极低出生体重儿的结局。
研究设计
作者对2000年至2009年入住一家新生儿重症监护病房（NICU）的孕20至24周的活产新生儿进行了一项回顾性队列研究。评估了结局死亡率及结局的预测因素。对双胎和单胎婴儿的结果进行了比较。
结果
该队列婴儿包括60名单胎婴儿和17对双胞胎。结果表明，与单胎相比，双胎的死亡风险增加。新生儿C反应蛋白（CRP）与入住NICU时细菌培养阳性结果之间的相关性可能是新生儿结局的一个预测因素。
结论
在极低出生体重儿中，双胎分娩与独立的死亡风险增加相关。头胎和二胎双胞胎的风险均增加。
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