一例伊维菌素成功治疗的女孩严重蠕形螨性眶周-面中部酒渣鼻
Severe demodexfolliculorum-associated oculocutaneous rosacea in a girl successfully treated with ivermectin.
机构信息
Department of Dermatology, School of Medicine, University of New Mexico, Albuquerque.
Department of Dermatology, Hospital Infantil del Niño Jesús, Madrid, Spain.
出版信息
JAMA Dermatol. 2014 Jan;150(1):61-3. doi: 10.1001/jamadermatol.2013.7688.
IMPORTANCE
There is a limited therapeutic armamentarium for recalcitrant cases of childhood rosacea.
OBSERVATIONS
We report the case of a 12-year-old girl who presented with severe ocular and cutaneous rosacea unresponsive to oral doxycycline, oral isotretinoin, and topical tacrolimus. A biopsy specimen showed numerous mites within the folliculosebaceous unit. Treatment with a single dose of oral ivermectin achieved resolution of her symptoms.
CONCLUSIONS AND RELEVANCE
The causative role of Demodex folliculorum should be considered in immunocompetent children with rosacea or rosacea-like refractory eruptions. In such cases, treatment with ivermectin can be beneficial.
重要性
对于顽固的儿童酒渣鼻病例，治疗方法有限。
观察结果
我们报告了一例 12 岁女孩的病例，她患有严重的眼部和皮肤酒渣鼻，对口服多西环素、口服异维 A 酸和外用他克莫司均无反应。活检标本显示在毛囊皮脂腺单位内有许多螨虫。单次口服伊维菌素治疗后，她的症状得到缓解。
结论和相关性
对于免疫功能正常的儿童，若出现酒渣鼻或类似酒渣鼻的难治性皮疹，应考虑毛囊蠕形螨的致病作用。在这种情况下，使用伊维菌素治疗可能有益。
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