核苷和核苷酸的质谱分析
Mass spectrometry analysis of nucleosides and nucleotides.
作者信息
Dudley Ed, Bond Liz
机构信息
Institute of Mass Spectrometry, College of Medicine, Swansea University, Singleton Park, Swansea, SA2 8PP, UK.
出版信息
Mass Spectrom Rev. 2014 Jul-Aug;33(4):302-31. doi: 10.1002/mas.21388. Epub 2013 Nov 27.
PMID:24285362
Abstract
Mass spectrometry has been widely utilised in the study of nucleobases, nucleosides and nucleotides as components of nucleic acids and as bioactive metabolites in their own right. In this review, the application of mass spectrometry to such analysis is overviewed in relation to various aspects regarding the analytical mass spectrometric and chromatographic techniques applied and also the various applications of such analysis.
摘要
质谱法已被广泛应用于核酸组成成分核碱基、核苷和核苷酸的研究，以及它们本身作为生物活性代谢物的研究。在本综述中，将从应用的分析质谱和色谱技术的各个方面以及此类分析的各种应用等方面概述质谱法在此类分析中的应用。
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