University of Tennessee Health Science Center College of Pharmacy, Memphis Campus, TN, USA.
Ann Pharmacother. 2013 Nov;47(11):1471-7. doi: 10.1177/1060028013504738.
Only 23% of patients are meeting all goals for cardiovascular complications of diabetes.
The purpose of our study is to evaluate the effect of a pharmacist-physician collaboration on attainment of cardiovascular-related goals in patients with type 2 diabetes.
This prospective, multicenter cohort enrolled patients from 7 practice sites that were members of the University of Tennessee Pharmacist Practice Based Research Network (UT Pharm Net). Patients were included if they were diagnosed with type 2 diabetes, at least 18 years of age and English speaking. Pregnant patients were excluded. Patients were followed for 12 months after enrollment. Primary cardiovascular outcomes included reduction in systolic blood pressure, diastolic blood pressure, and low-density lipoprotein (LDL) as well as the proportion of patients achieving a blood pressure goal of <130/80 mm Hg and proportion of patients achieving an LDL goal of <100 mg/dL.
For the 206 patients enrolled, the average age was 59.7 years; the majority were male (59.7%) and white (66%). When compared with baseline, the postintervention mean systolic (P < .0001), diastolic blood pressure (P = .0003), and LDL (P < .0001) decreased significantly. The proportion of patients achieving a blood pressure of <130/80 mm Hg increased 21.8% (P < .0001), and the proportion of patients achieving an LDL of <100 mg/dL increased 12% (P = .0023).
The results of our study indicate that collaborative management has a positive impact on decreasing cardiovascular risk and assists patients in attaining national goals for blood pressure and cholesterol.
仅有 23%的患者达到了糖尿病心血管并发症的所有目标。
我们的研究旨在评估药师-医师合作对 2 型糖尿病患者实现心血管相关目标的影响。
这项前瞻性、多中心队列研究纳入了来自田纳西大学药师实践基础研究网络(UT Pharm Net)的 7 个实践站点的患者。患者入选标准为:诊断为 2 型糖尿病,年龄至少 18 岁,且能说英语。排除妊娠患者。患者在入组后随访 12 个月。主要心血管结局包括收缩压、舒张压和低密度脂蛋白(LDL)的降低,以及达到血压目标<130/80mmHg 的患者比例和达到 LDL 目标<100mg/dL 的患者比例。
在纳入的 206 例患者中,平均年龄为 59.7 岁;大多数为男性(59.7%)和白人(66%)。与基线相比,干预后平均收缩压(P<0.0001)、舒张压(P=0.0003)和 LDL(P<0.0001)显著降低。达到血压<130/80mmHg 的患者比例增加了 21.8%(P<0.0001),达到 LDL<100mg/dL 的患者比例增加了 12%(P=0.0023)。
我们的研究结果表明,协作管理对降低心血管风险有积极影响,并有助于患者达到血压和胆固醇的国家目标。