College of Pharmacy, Health Science Center, University of Tennessee, Knoxville Campus, Knoxville, TN, USA.
Ann Pharmacother. 2013 Jun;47(6):781-9. doi: 10.1345/aph.1S079. Epub 2013 May 8.
Multiple complications can arise secondary to poor control of glucose, blood pressure, and cholesterol in a patient with diabetes.
To evaluate the effect of a pharmacist-physician collaboration on attainment of diabetes-related measures of control.
This was a prospective, multicenter, cohort study. Patients were enrolled from 7 practice sites throughout Tennessee if they had been diagnosed with type 2 diabetes, were aged 18 years or older with a life expectancy greater than 1 year, and were English speaking. Pregnant women were excluded. Patients were followed for 12 months following enrollment by informed consent. The pharmacist-physician collaboration method was established prior to study initiation. Primary outcomes included hemoglobin A1c (A1C), number of patients with A1C less than 7%, and percentage of patients with A1C greater than 9%.
Of the 206 patients enrolled, the mean age was 59.73 years, and most were male (59.71%) and white (66.02%). The A1C was reduced by an average of 1.16% (p < 0.0001). The proportion of patients with A1C less than 7% increased from 12.75% at baseline to 36.76% at study conclusion (p = 0.0002). The proportion of patients with A1C greater than 9% decreased from 34.15% to 16.50%, (p < 0.0001).
Pharmacist-physician collaborative management at multiple practice locations and types of setting (eg, private, academic, Veterans Affairs medical center) has a positive impact on glycemic control and diabetes-related health maintenance. This was accomplished without increasing the total number of antihyperglycemic agents prescribed and without an increase in patient-reported episodes of hypoglycemia.
糖尿病患者如果血糖、血压和胆固醇控制不佳，可能会出现多种并发症。
评估药师-医师合作对实现糖尿病相关控制指标的影响。
这是一项前瞻性、多中心、队列研究。如果患者被诊断患有 2 型糖尿病、年龄在 18 岁及以上且预期寿命超过 1 年且会讲英语，他们将从田纳西州的 7 个诊所中被纳入研究。孕妇被排除在外。患者在入组后通过知情同意进行为期 12 个月的随访。在研究开始前建立了药师-医师合作方法。主要结局包括糖化血红蛋白（A1C）、A1C 小于 7%的患者数量以及 A1C 大于 9%的患者百分比。
在 206 名入组患者中，平均年龄为 59.73 岁，大多数为男性（59.71%）和白人（66.02%）。A1C 平均降低了 1.16%（p<0.0001）。A1C 小于 7%的患者比例从基线时的 12.75%增加到研究结束时的 36.76%（p=0.0002）。A1C 大于 9%的患者比例从 34.15%降至 16.50%（p<0.0001）。
在多个实践地点和多种环境（如私人、学术、退伍军人事务医疗中心）中进行药师-医师协作管理对血糖控制和糖尿病相关的健康维护具有积极影响。这是在不增加开处的降血糖药物总数的情况下，并且在没有增加患者报告的低血糖发作的情况下实现的。
