Nikolova E B
Haematologia (Budap). 1986;19(2):133-40.
The cellular distribution of two anti-HLA-DR-like monoclonal antibodies was examined. The reagents showed typical affinity to E- cells, adherent cells and activated T cells. Functionally, they affected the presentation of PPD antigen from APC to T cells in autologous and allogeneic mixed lymphocyte reaction. One of them significantly influenced the proliferation of T helper cells activated polyclonally with PHA.
检测了两种抗HLA-DR样单克隆抗体的细胞分布。这些试剂对E细胞、贴壁细胞和活化的T细胞表现出典型的亲和力。在功能上,它们在自体和异体混合淋巴细胞反应中影响了抗原呈递细胞向T细胞呈递PPD抗原的过程。其中一种抗体显著影响了用PHA多克隆激活的辅助性T细胞的增殖。