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当前关于器官捐献者管理的研究。

Current research on organ donor management.

作者信息

Sally Mitchell, Malinoski Darren

机构信息

Portland VA Medical Center, Oregon Health & Science University, PO Box 1034/Mail Code P3ANES, Portland, OR 97207, USA.

出版信息

Anesthesiol Clin. 2013 Dec;31(4):737-48. doi: 10.1016/j.anclin.2013.08.004. Epub 2013 Nov 1.

DOI:10.1016/j.anclin.2013.08.004
PMID:24287350
Abstract

A shortage of organs is available for transplantation, with 116,000 patients on the Organ Procurement and Transplantation Network/United Network for Organ Sharing wait list. Because the demand for organs outweighs the supply, considerable care must be taken to maximize the number of organs transplanted per donor and optimize the quality of recovered organs. Studies designed to determine optimal donor management therapies are limited, and this research has many challenges. Although evidenced-based guidelines for managing potential organ donors do not exist, research in this area is increasing. This article reviews the existing literature and highlights recent trials that can guide management.

摘要

可供移植的器官短缺,器官获取与移植网络/器官共享联合网络的等待名单上有11.6万名患者。由于器官需求超过供应,必须格外谨慎,以最大限度地增加每位捐赠者移植的器官数量,并优化获取器官的质量。旨在确定最佳捐赠者管理疗法的研究有限,且这项研究面临诸多挑战。虽然不存在管理潜在器官捐赠者的循证指南,但该领域的研究正在增加。本文回顾了现有文献,并重点介绍了可指导管理的近期试验。

相似文献

1
Current research on organ donor management.当前关于器官捐献者管理的研究。
Anesthesiol Clin. 2013 Dec;31(4):737-48. doi: 10.1016/j.anclin.2013.08.004. Epub 2013 Nov 1.
2
The impact of meeting donor management goals on the number of organs transplanted per expanded criteria donor: a prospective study from the UNOS Region 5 Donor Management Goals Workgroup.符合供体管理目标对每位扩大标准供体移植器官数量的影响:来自 UNOS 地区 5 供体管理目标工作组的前瞻性研究。
JAMA Surg. 2014 Sep;149(9):969-75. doi: 10.1001/jamasurg.2014.967.
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The impact of meeting donor management goals on the number of organs transplanted per donor: results from the United Network for Organ Sharing Region 5 prospective donor management goals study.会议捐赠者管理目标对每位捐赠者移植器官数量的影响:来自美国器官共享联合网络地区 5 前瞻性捐赠者管理目标研究的结果。
Crit Care Med. 2012 Oct;40(10):2773-80. doi: 10.1097/CCM.0b013e31825b252a.
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Achieving donor management goals before deceased donor procurement is associated with more organs transplanted per donor.在已故供体获取前实现供体管理目标与每位供体移植更多器官相关。
J Trauma. 2011 Oct;71(4):990-5; discussion 996. doi: 10.1097/TA.0b013e31822779e5.
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Aggressive organ donor management protocol.积极的器官捐献者管理方案。
J Intensive Care Med. 2008 Nov-Dec;23(6):367-75. doi: 10.1177/0885066608324208. Epub 2008 Sep 24.
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The reward is worth the wait: a prospective analysis of 100 consecutive organ donors.等待是值得的:对100例连续器官捐献者的前瞻性分析。
Am Surg. 2012 Mar;78(3):296-9.
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Taking values seriously: Ethical challenges in organ donation and transplantation for critical care professionals.重视价值观:重症护理专业人员在器官捐赠与移植中的伦理挑战。
Crit Care Med. 2007 Feb;35(2 Suppl):S95-101. doi: 10.1097/01.CCM.0000252915.76019.19.
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Sequential improvements in organ procurement increase the organ donation rate.器官获取的连续改进提高了器官捐献率。
Injury. 2012 Nov;43(11):1805-10. doi: 10.1016/j.injury.2012.08.012. Epub 2012 Aug 22.
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Expanding the donor pool: use of marginal donors for solid organ transplantation.扩大供体库:边缘供体在实体器官移植中的应用。
Clin Transplant. 1996 Feb;10(1 Pt 1):1-19.
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Outcomes of management for potential deceased donors.潜在已故捐赠者的管理结果。
Transplant Proc. 2012 May;44(4):843-7. doi: 10.1016/j.transproceed.2012.01.102.

引用本文的文献

1
A multicenter randomized placebo-controlled trial of intravenous thyroxine for heart-eligible brain-dead organ donors.多中心随机安慰剂对照试验静脉注射甲状腺素治疗适合心脏的脑死亡器官捐献者。
Trials. 2021 Nov 27;22(1):852. doi: 10.1186/s13063-021-05797-2.
2
Causes of Deceased Donors Loss before Organ Retrieval.器官获取前死亡供体流失的原因。
Tanaffos. 2018 Mar;17(3):172-176.
3
Development of key interventions and quality indicators for the management of an adult potential donor after brain death: a RAND modified Delphi approach.
脑死亡后成年潜在供体管理的关键干预措施及质量指标的制定:兰德改良德尔菲法
BMC Health Serv Res. 2018 Jul 24;18(1):580. doi: 10.1186/s12913-018-3386-1.