Sally Mitchell, Malinoski Darren
Portland VA Medical Center, Oregon Health & Science University, PO Box 1034/Mail Code P3ANES, Portland, OR 97207, USA.
Anesthesiol Clin. 2013 Dec;31(4):737-48. doi: 10.1016/j.anclin.2013.08.004. Epub 2013 Nov 1.
A shortage of organs is available for transplantation, with 116,000 patients on the Organ Procurement and Transplantation Network/United Network for Organ Sharing wait list. Because the demand for organs outweighs the supply, considerable care must be taken to maximize the number of organs transplanted per donor and optimize the quality of recovered organs. Studies designed to determine optimal donor management therapies are limited, and this research has many challenges. Although evidenced-based guidelines for managing potential organ donors do not exist, research in this area is increasing. This article reviews the existing literature and highlights recent trials that can guide management.
可供移植的器官短缺,器官获取与移植网络/器官共享联合网络的等待名单上有11.6万名患者。由于器官需求超过供应,必须格外谨慎,以最大限度地增加每位捐赠者移植的器官数量,并优化获取器官的质量。旨在确定最佳捐赠者管理疗法的研究有限,且这项研究面临诸多挑战。虽然不存在管理潜在器官捐赠者的循证指南,但该领域的研究正在增加。本文回顾了现有文献,并重点介绍了可指导管理的近期试验。