Schwab W, Ries G, Handschuh K
HNO. 1986 Aug;34(8):327-33.
The local control rates for previously irradiated recurrent tumours of the head and neck is dose dependent. High dose percutaneous irradiation alone is associated with a high complication rate. On the other hand it is possible to apply high local doses by interstitial irradiation, whilst sparing the surrounding tissue. In the last 2 years we have used Iodine 125-seeds in carrier (Vicryl) and a high dose rate Iridium 192-source for the afterloading technique. Our first experiences with 12 patients show reasonable palliation, but not effect on survival.
头颈部既往接受过放疗的复发性肿瘤的局部控制率取决于剂量。单纯高剂量经皮照射会伴有较高的并发症发生率。另一方面，通过组织间照射有可能给予高局部剂量，同时使周围组织免受损伤。在过去两年中，我们使用了载于载体（聚乙交酯纤维）中的碘125种子源和高剂量率铱192源进行后装技术。我们对12例患者的初步经验显示有合理的姑息效果，但对生存率无影响。
