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[头颈部肿瘤姑息治疗中组织间近距离后装治疗的初步经验(载体/维克牢尼龙搭扣中低剂量率碘-125籽源和高剂量率铱-192后装系统)]

[Initial experiences with interstitial brachycurietherapy (low dose rate I-125 seeds in carrier/vicryl and high dose rate Ir-192 afterloading system) in the palliative treatment of head and neck tumors].

作者信息

Schwab W, Ries G, Handschuh K

出版信息

HNO. 1986 Aug;34(8):327-33.

PMID:2428779
Abstract

The local control rates for previously irradiated recurrent tumours of the head and neck is dose dependent. High dose percutaneous irradiation alone is associated with a high complication rate. On the other hand it is possible to apply high local doses by interstitial irradiation, whilst sparing the surrounding tissue. In the last 2 years we have used Iodine 125-seeds in carrier (Vicryl) and a high dose rate Iridium 192-source for the afterloading technique. Our first experiences with 12 patients show reasonable palliation, but not effect on survival.

摘要

头颈部既往接受过放疗的复发性肿瘤的局部控制率取决于剂量。单纯高剂量经皮照射会伴有较高的并发症发生率。另一方面,通过组织间照射有可能给予高局部剂量,同时使周围组织免受损伤。在过去两年中,我们使用了载于载体(聚乙交酯纤维)中的碘125种子源和高剂量率铱192源进行后装技术。我们对12例患者的初步经验显示有合理的姑息效果,但对生存率无影响。

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