Eris Cuneyt, Yavuz Senol, Yalcinkaya Serhat, Gucu Arif, Toktas Faruk, Yumun Gunduz, Erdolu Burak, Ozyazıcıoglu Ahmet
Departments of Cardiovascular Surgery, Bursa Yuksek Ihtisas Education and Research Hospital, 16330 Bursa, Turkey.
ScientificWorldJournal. 2013 Oct 27;2013:631534. doi: 10.1155/2013/631534. eCollection 2013.
Acute mesenteric ischemia (AMI) is a rare but serious complication after cardiac surgery. The aim of this retrospective study was to evaluate the incidence, outcome, and perioperative risk factors of AMI in the patients undergoing elective cardiac surgery.
From January 2005 to May 2013, all patients who underwent cardiac surgery were screened for participation, and patients with registered gastrointestinal complications were retrospectively reviewed. Univariate analyses were performed.
The study included 6013 patients, of which 52 (0.86%) patients suffered from AMI, 35 (67%) of whom died. The control group (150 patients) was randomly chosen from among cases undergoing cardiopulmonary bypass (CPB). Preoperative parameters including age (P = 0.03), renal insufficiency (P = 0.004), peripheral vascular disease (P = 0.04), preoperative inotropic support (P < 0.001), poor left ventricular ejection fraction (P = 0.002), cardiogenic shock (P = 0.003), and preoperative intra-aortic balloon pump (IABP) support (P = 0.05) revealed significantly higher levels in the AMI group. Among intra- and postoperative parameters, CPB time (P < 0.001), dialysis (P = 0.04), inotropic support (P = 0.007), prolonged ventilator time (P < 0.001), and IABP support (P = 0.007) appeared significantly higher in the AMI group than the control group.
Prompt diagnosis and early treatment should be initiated as early as possible in any patient suspected of AMI, leading to dramatic reduction in the mortality rate.
急性肠系膜缺血(AMI)是心脏手术后一种罕见但严重的并发症。本回顾性研究的目的是评估择期心脏手术患者中AMI的发生率、结局及围手术期危险因素。
2005年1月至2013年5月,对所有接受心脏手术的患者进行参与筛查,并对登记有胃肠道并发症的患者进行回顾性分析。进行单因素分析。
该研究纳入6013例患者,其中52例(0.86%)发生AMI,35例(67%)死亡。对照组(150例患者)从接受体外循环(CPB)的病例中随机选取。术前参数包括年龄(P = 0.03)、肾功能不全(P = 0.004)、外周血管疾病(P = 0.04)、术前使用血管活性药物支持(P < 0.001)、左心室射血分数低(P = 0.002)、心源性休克(P = 0.003)及术前主动脉内球囊反搏(IABP)支持(P = 0.05),在AMI组中显著更高。在术中和术后参数中,AMI组的CPB时间(P < 0.001)、透析(P = 0.04)、血管活性药物支持(P = 0.007)、机械通气时间延长(P < 0.001)及IABP支持(P = 0.007)均显著高于对照组。
对于任何疑似AMI的患者,应尽早进行快速诊断和早期治疗,从而显著降低死亡率。