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嗜铬细胞瘤危象：两例在择期非相关外科手术后出现的未确诊嗜铬细胞瘤病例。

Phaeochromocytoma crisis: two cases of undiagnosed phaeochromocytoma presenting after elective nonrelated surgical procedures.

作者信息

Johnston P C, Silversides J A, Wallace H, Farling P A, Hutchinson A, Hunter S J, Eatock F, Mullan K R

机构信息

Regional Centre for Endocrinology and Diabetes, Royal Victoria Hospital, Grosvenor Road, Belfast BT12 6BA, UK.

出版信息

Case Rep Anesthesiol. 2013;2013:514714. doi: 10.1155/2013/514714. Epub 2013 Oct 28.

DOI:10.1155/2013/514714
PMID:24288628
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3830875/
Abstract

Phaeochromocytoma is a catecholamine producing tumour and an uncommon cause of hypertension. We present two cases of relatively asymptomatic individuals, in which previously undiagnosed phaeochromocytoma was unmasked by elective nonadrenal surgical procedures, manifesting as postoperative hypertensive crisis and subsequent cardiogenic shock. The initial management in intensive care is discussed, in addition to the clinical and biochemical diagnostic challenges present. Successful adrenalectomy was performed in each case.

摘要

嗜铬细胞瘤是一种分泌儿茶酚胺的肿瘤，是高血压的罕见病因。我们报告两例相对无症状的患者，在择期非肾上腺外科手术中，先前未被诊断出的嗜铬细胞瘤被发现，表现为术后高血压危象及随后的心源性休克。除了所面临的临床和生化诊断挑战外，还讨论了重症监护中的初始管理。两例患者均成功进行了肾上腺切除术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f36/3830875/56038df0fe2b/CRIM.ANESTHESIOLOGY2013-514714.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f36/3830875/56038df0fe2b/CRIM.ANESTHESIOLOGY2013-514714.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f36/3830875/56038df0fe2b/CRIM.ANESTHESIOLOGY2013-514714.001.jpg

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本文引用的文献

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Intraoperative management of patients with incidental catecholamine producing tumors: A literature review and analysis.偶发性儿茶酚胺分泌肿瘤患者的术中管理：文献综述与分析
J Anaesthesiol Clin Pharmacol. 2013 Jan;29(1):41-6. doi: 10.4103/0970-9185.105793.
2
Perioperative management of pheochromocytoma: the heart of the issue.嗜铬细胞瘤的围手术期管理：问题的核心
Minerva Endocrinol. 2013 Mar;38(1):77-93.
3
Pheochromocytoma crisis is not a surgical emergency.嗜铬细胞瘤危象不是手术急症。
副神经节瘤表现为应激性心肌病：病例报告及文献综述
Endocrinol Diabetes Metab Case Rep. 2019 Apr 16;2019. doi: 10.1530/EDM-19-0017.
4
A malignant looking "renal" mass is not always renal cancer.外观可疑的“肾脏”肿物并不一定都是肾癌。
Urol Case Rep. 2018 Feb 3;17:128-130. doi: 10.1016/j.eucr.2018.01.020. eCollection 2018 Mar.
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Extracorporeal membrane oxygenation for pheochromocytoma-induced cardiogenic shock.体外膜肺氧合用于嗜铬细胞瘤诱发的心源性休克
Ann Intensive Care. 2016 Dec;6(1):117. doi: 10.1186/s13613-016-0219-4. Epub 2016 Nov 28.
6
Recurrence of Phaeochromocytoma and Abdominal Paraganglioma After Initial Surgical Intervention.初次手术干预后嗜铬细胞瘤和腹部副神经节瘤的复发
Ulster Med J. 2015 May;84(2):102-6.
J Clin Endocrinol Metab. 2013 Feb;98(2):581-91. doi: 10.1210/jc.2012-3020. Epub 2013 Jan 2.
4
Pheochromocytoma-induced reverse tako-tsubo with rapid recovery of left ventricular function.嗜铬细胞瘤诱发的逆性 Takotsubo 心肌病伴左心室功能快速恢复。
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Ann Thorac Surg. 2012 Apr;93(4):1303-5. doi: 10.1016/j.athoracsur.2011.09.018.
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