Yedinak Chris, Brzana Jessica, Fleseriu Maria
Northwest Pituitary Center, 3303 SW Bond Avenue, Portland, OR 97239, USA ; Department of Neurosurgery, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.
Case Rep Endocrinol. 2013;2013:735489. doi: 10.1155/2013/735489. Epub 2013 Oct 31.
Cushing's disease (CD) is a disorder in which chronic excess adrenocorticotropic hormone production is associated with multiple comorbidities and diminished quality of life. Postsurgical monitoring is important, and newer therapies are available for the management of surgical failure or disease recurrence. In this clinical case, we illustrate the importance of the nursing role in long-term management of CD, particularly as nurses may be the first point of contact for patients with CD. Alertness to disease signs and symptoms is crucial for timely diagnosis and improved outcomes. Successful therapy for CD requires careful monitoring of hormonal control, metabolic parameters, and therapy complications. Ongoing management requires lifelong monitoring of metabolic parameters, of side effects of treatment, and of signs of disease recurrence. Appropriate referrals may be required to facilitate overall outcomes and patient wellbeing. This patient was enrolled in a Phase III trial that was registered in the USA with clinicaltrial.gov.
库欣病（CD）是一种慢性促肾上腺皮质激素分泌过多并伴有多种合并症及生活质量下降的疾病。术后监测很重要，并且有新的疗法可用于治疗手术失败或疾病复发。在本临床病例中，我们阐述了护理在库欣病长期管理中的重要作用，特别是因为护士可能是库欣病患者的首个接触点。对疾病体征和症状保持警觉对于及时诊断和改善预后至关重要。库欣病的成功治疗需要仔细监测激素控制、代谢参数和治疗并发症。持续管理需要对代谢参数、治疗副作用和疾病复发迹象进行终身监测。可能需要进行适当的转诊以促进整体预后和患者健康。该患者参加了一项在美国clinicaltrial.gov注册的III期试验。
