Lü Xing, Yu Wei-juan, Lan Ya-qiong, Li Li, Lü Sheng, Ye Zhao-xia, Zhang Yong-ming, Liu Rui, Chen Lü-jun
College of Life and Environmental Science, Shanghai Normal University, Shanghai 200234, China.
Huan Jing Ke Xue. 2013 Sep;34(9):3368-73.
Liquid chromatography and tandem mass (LC-MS/MS) followed with solid-phase extraction (SPE) was developed for simultaneously determining four classes (tetracyclines, quinolones, macrolides and sulfonamides) of ten commonly used veterinary antibiotics in groundwater of Jiaxing city, an important pig breeding base in the Yangtze River Delta region. Samples were taken from 10 typical rural river sections and 21 main urban river sections. Results revealed severe pollution existed in the rural river environment. The total concentration of ten antibiotics was as high as 65.6-467.0 ng x L(-1), among which tetracyclines and sulfonamides respectively ranged in 40.8-253.0 ng x L(-1) and undetected (nd)- 165.0 ng x L(-1), macrolides and quinolones respectively ranged in 3.1-14.68 ng x L(-1) and nd-14.54 ng x L(-1). By comparison, the pollution level in urban rivers was much lower. The total concentration of ten antibiotics ranged in 20.1 ng x L(-1) to 61.2 ng x L(-1), among with tetracyclines varied from undetected to 44.0 ng x L(-1), while sulfonamides, macrolides and quinolones were respectively below 2.7 ng x L(-1), 6.3 ng x L(-1) and 21.6 ng x L(-1).
采用液相色谱-串联质谱法（LC-MS/MS）结合固相萃取法（SPE），同时测定长江三角洲地区重要养猪基地嘉兴市地下水中10种常用兽用抗生素的4类（四环素类、喹诺酮类、大环内酯类和磺胺类）。从10个典型农村河段和21个城市主要河段采集样本。结果显示农村河流环境存在严重污染。10种抗生素的总浓度高达65.6 - 467.0 ng·L⁻¹，其中四环素类和磺胺类分别在40.8 - 253.0 ng·L⁻¹和未检出（nd）- 165.0 ng·L⁻¹范围内，大环内酯类和喹诺酮类分别在3.1 - 14.68 ng·L⁻¹和nd - 14.54 ng·L⁻¹范围内。相比之下，城市河流的污染水平要低得多。10种抗生素的总浓度在20.1 ng·L⁻¹至61.2 ng·L⁻¹之间，其中四环素类未检出至44.0 ng·L⁻¹不等，而磺胺类、大环内酯类和喹诺酮类分别低于2.7 ng·L⁻¹、6.3 ng·L⁻¹和21.6 ng·L⁻¹。
