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修订后的心脏风险指数能否预测择期肺切除术后的心脏并发症?

Does the revised cardiac risk index predict cardiac complications following elective lung resection?

作者信息

Wotton Robin, Marshall Andrea, Kerr Amy, Bishay Ehab, Kalkat Maninder, Rajesh Pala, Steyn Richard, Naidu Babu, Abdelaziz Mahmoud, Hussain Khalid

机构信息

Department of Thoracic Surgery, Heart of England NHS Foundation Trust, Bordesley Green East, Birmingham B9 5SS, UK.

出版信息

J Cardiothorac Surg. 2013 Dec 1;8:220. doi: 10.1186/1749-8090-8-220.

Abstract

BACKGROUND

Revised Cardiac Risk Index (RCRI) score and Thoracic Revised Cardiac Risk Index (ThRCRI) score were developed to predict the risks of postoperative major cardiac complications in generic surgical population and thoracic surgery respectively. This study aims to determine the accuracy of these scores in predicting the risk of developing cardiac complications including atrial arrhythmias after lung resection surgery in adults.

METHODS

We studied 703 patients undergoing lung resection surgery in a tertiary thoracic surgery centre. Observed outcome measures of postoperative cardiac morbidity and mortality were compared against those predicted by risk.

RESULTS

Postoperative major cardiac complications and supraventricular arrhythmias occurred in 4.8% of patients. Both index scores had poor discriminative ability for predicting postoperative cardiac complications with an area under receiver operating characteristic (ROC) curve of 0.59 (95% CI 0.51-0.67) for the RCRI score and 0.57 (95% CI 0.49-0.66) for the ThRCRI score.

CONCLUSIONS

In our cohort, RCRI and ThRCRI scores failed to accurately predict the risk of cardiac complications in patients undergoing elective resection of lung cancer. The British Thoracic Society (BTS) recommendation to seek a cardiology referral for all asymptomatic pre-operative lung resection patients with > 3 RCRI risk factors is thus unlikely to be of clinical benefit.

摘要

背景

修订心脏风险指数(RCRI)评分和胸科修订心脏风险指数(ThRCRI)评分分别用于预测普通外科人群和胸科手术术后主要心脏并发症的风险。本研究旨在确定这些评分在预测成人肺切除术后发生包括房性心律失常在内的心脏并发症风险方面的准确性。

方法

我们研究了一家三级胸科手术中心的703例接受肺切除手术的患者。将术后心脏发病率和死亡率的观察结果与风险预测结果进行比较。

结果

4.8%的患者发生了术后主要心脏并发症和室上性心律失常。两种指数评分在预测术后心脏并发症方面的判别能力较差,RCRI评分的受试者工作特征(ROC)曲线下面积为0.59(95%CI 0.51 - 0.67),ThRCRI评分为0.57(95%CI 0.49 - 0.66)。

结论

在我们的队列中,RCRI和ThRCRI评分未能准确预测择期肺癌切除患者的心脏并发症风险。因此,英国胸科学会(BTS)建议对所有术前无症状且RCRI风险因素>3的肺切除患者进行心脏病转诊,这可能不会带来临床益处。

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