细针穿刺细胞学检查在12岁以下儿童颈部淋巴结病患者中的临床价值
Clinical value of fine needle aspiration cytology in pediatric cervical lymphadenopathy patients under 12-years-of-age.
作者信息
Lee Dong Hoon, Baek Hee Jo, Kook Hoon, Yoon Tae Mi, Lee Joon Kyoo, Lim Sang Chul
机构信息
Department of Otolaryngology-Head and Neck Surgery Chonnam National University Medical School & Hwasun Hospital, Hwasun, South Korea.
Department of Pediatrics, Chonnam National University Medical School & Hwasun Hospital, Hwasun, South Korea.
出版信息
Int J Pediatr Otorhinolaryngol. 2014 Jan;78(1):79-81. doi: 10.1016/j.ijporl.2013.10.054. Epub 2013 Nov 14.
OBJECTIVE
The purpose of this study was to evaluate the usefulness and accuracy of fine needle aspiration cytology (FNAC) in the diagnosis of pediatric cervical lymphadenopathy in patients under 12-years-of-age.
METHODS
A retrospective chart review was performed to evaluate patients under 12-years-of-age with cervical lymphadenopathy who underwent lymph node excision biopsy from January 2007 to June 2013. The results of FNAC were compared them with the corresponding histopathological diagnosis.
RESULTS
Eighteen of the 27 patients had undergone FNAC before performing excision biopsy, which diagnosed benign diseases in 15 patients and malignant diseases in three patients. All 18 patients underwent excision biopsy. FNAC had a diagnostic sensitivity of 100%, positive-predictive value of 93.3%, and accuracy of 94.5% for diagnosing pediatric cervical lymphadenopathy.
CONCLUSIONS
FNAC is a useful and accurate adjunct for the evaluation of pediatric cervical lymphadenopathy. FNAC should be part of the initial evaluation of pediatric patients with cervical lymphadenopathy before determining the treatment plan.
目的
本研究旨在评估细针穿刺细胞学检查（FNAC）在诊断12岁以下儿童颈部淋巴结病中的实用性和准确性。
方法
进行一项回顾性病历审查，以评估2007年1月至2013年6月期间接受淋巴结切除活检的12岁以下颈部淋巴结病患者。将FNAC的结果与相应的组织病理学诊断结果进行比较。
结果
27例患者中有18例在进行切除活检前接受了FNAC检查，其中15例诊断为良性疾病，3例诊断为恶性疾病。所有18例患者均接受了切除活检。FNAC对儿童颈部淋巴结病的诊断敏感性为100%，阳性预测值为93.3%，准确性为94.5%。
结论
FNAC是评估儿童颈部淋巴结病的一种有用且准确的辅助方法。在确定治疗方案之前，FNAC应作为儿童颈部淋巴结病初始评估的一部分。
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