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两阶段翻修术治疗感染性全肘人工关节置换术后翻修。

Two-stage revision for the treatment of the infected total elbow arthroplasty.

机构信息

University Hospital of South Manchester, Shoulder and Elbow Unit, Southmoor Road, Wythenshawe, Manchester M23 9LT, UK.

出版信息

Bone Joint J. 2013 Dec;95-B(12):1681-6. doi: 10.1302/0301-620X.95B12.31336.

Abstract

We report our experience of staged revision surgery for the treatment of infected total elbow arthroplasty (TEA). Between 1998 and 2010 a consecutive series of 33 patients (34 TEAs) underwent a first-stage procedure with the intention to proceed to second-stage procedure when the infection had been controlled. A single first-stage procedure with removal of the components and cement was undertaken for 29 TEAs (85%), followed by the insertion of antibiotic-impregnated cement beads, and five (15%) required two or more first-stage procedures. The most common organism isolated was coagulase-negative Staphylococcus in 21 TEAs (62%). A second-stage procedure was performed for 26 TEAs (76%); seven patients (seven TEAs, 21%) had a functional resection arthroplasty with antibiotic beads in situ and had no further surgery, one had a persistent discharge preventing further surgery. There were three recurrent infections (11.5%) in those patients who underwent a second-stage procedure. The infection presented at a mean of eight months (5 to 10) post-operatively. The mean Mayo Elbow Performance Score (MEPS) in those who underwent a second stage revision without recurrent infection was 81.1 (65 to 95). Staged revision surgery is successful in the treatment of patients with an infected TEA and is associated with a low rate of recurrent infection. However, when infection does occur, this study would suggest that it becomes apparent within ten months of the second stage procedure.

摘要

我们报告了分期翻修手术治疗感染性全肘关节置换术(TEA)的经验。1998 年至 2010 年间,连续有 33 例患者(34 例 TEA)接受了一期手术,目的是在感染得到控制后进行二期手术。29 例 TEA(85%)采用了单一的一期手术,即切除假体和骨水泥,然后插入抗生素骨水泥珠,5 例(15%)需要进行两次或更多次一期手术。最常见的分离病原体为 21 例 TEA(62%)中的凝固酶阴性葡萄球菌。26 例 TEA(76%)进行了二期手术;7 例患者(7 例 TEA,21%)进行了带抗生素珠的功能性切除关节成形术,无需进一步手术,1 例因持续排液而无法进行进一步手术。在接受二期手术的患者中,有 3 例(11.5%)出现了复发性感染。感染发生在术后平均 8 个月(5 至 10 个月)。在无复发性感染的二期翻修患者中,Mayo 肘关节功能评分(MEPS)平均为 81.1(65 至 95)。分期翻修手术是治疗感染性 TEA 的有效方法,其复发性感染率较低。然而,当感染确实发生时,本研究表明它会在二期手术后的十个月内显现出来。

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