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二期翻修治疗感染性肘关节炎假体。

The management of infected elbow arthroplasty by two-stage revision.

机构信息

Shoulder & Elbow Unit, Royal National Orthopaedic Hospital, Stanmore, Middlesex, UK.

Shoulder & Elbow Unit, Royal National Orthopaedic Hospital, Stanmore, Middlesex, UK.

出版信息

J Shoulder Elbow Surg. 2018 May;27(5):879-886. doi: 10.1016/j.jse.2017.12.033. Epub 2018 Mar 1.

DOI:10.1016/j.jse.2017.12.033
PMID:29503100
Abstract

BACKGROUND

Deep prosthetic infection is a potentially devastating complication after total elbow arthroplasty, with an incidence of up to 12%. This study examined the demographics, microbiologic profile, and outcomes of infected total elbow arthroplasty treated with 2-stage revision in a tertiary referral unit.

METHODS

We identified 19 consecutive patients (mean age, 65 years) undergoing revision arthroplasty for deep prosthetic infection. All patients underwent a first-stage procedure with removal of implants, débridement, and insertion of an antibiotic-loaded cement spacer, followed by at least 6 weeks of intravenous antibiotics. Fourteen patients required a second-stage revision.

RESULTS

Five patients did not undergo a second-stage procedure because of patient choice (n = 2), medical or surgical risk factors (n = 2), and death from an unrelated cause (n = 1). Of the 19 patients undergoing a first-stage procedure, 16 (84%) remained infection free, and 11 of the 14 patients (79%) undergoing reimplantation of an elbow prosthesis remained infection free. Six patients required further surgery (3 for recurrent infection, 3 for noninfective indications). The commonest infecting organism was Staphylococcus aureus (47%). A degree of postoperative ulnar nerve dysfunction occurred in 37% of patients, but all resolved fully without further treatment.

CONCLUSIONS

Management of prosthetic joint infection using 2-stage revision can result in high rates of eradication, although rates of reoperation and transient ulnar nerve dysfunction are high.

摘要

背景

全肘关节置换术后深部假体感染是一种潜在的破坏性并发症,发生率高达 12%。本研究在一家三级转诊中心检查了经两阶段翻修治疗的感染性全肘关节置换术的人口统计学、微生物学特征和结果。

方法

我们确定了 19 例连续患者(平均年龄 65 岁),他们因深部假体感染而行翻修关节置换术。所有患者均行一期手术,包括取出植入物、清创和插入载抗生素的水泥间隔物,然后至少静脉内使用 6 周抗生素。14 例患者需要进行二期翻修。

结果

由于患者选择(n=2)、医疗或手术危险因素(n=2)以及与感染无关的死亡(n=1),有 5 例患者未进行二期手术。在接受一期手术的 19 例患者中,16 例(84%)无感染,14 例接受肘关节假体再植入的患者中有 11 例(79%)无感染。6 例患者需要进一步手术(3 例因复发性感染,3 例因非感染性指征)。最常见的感染病原体是金黄色葡萄球菌(47%)。37%的患者出现术后尺神经功能障碍,但所有患者均完全无需进一步治疗而得到缓解。

结论

使用两阶段翻修治疗假体关节感染可实现高清除率,但再手术率和短暂性尺神经功能障碍率较高。

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