Jiang Shengyang, Jiang Donglin, Tao Yijia
Department of Cardiology, the Third Affiliated Hospital to Nantong University, Wuxi, Jiangsu Province, China.
Exp Clin Cardiol. 2013 Winter;18(1):53-6.
Cardiovascular diseases are threatening human health with rising morbidity and mortality rates. Gamma-glutamyltransferase (GGT) has been found to be involved in the pathogenesis of cardiovascular diseases, especially coronary artery disease, and the prognosis of cardiovascular disease may be predicted by increasing GGT levels. GGT levels are related to cardiovascular emergencies of chronic heart failure, and an elevated GGT level has been shown to be an independent predictive maker for cardiac death and cardiac transplantation. Investigation of the role of GGT in the mechanism of cardiac diseases will be helpful in developing preventive strategies and treatment methods.
心血管疾病的发病率和死亡率不断上升,正威胁着人类健康。γ-谷氨酰转移酶(GGT)已被发现参与心血管疾病的发病机制,尤其是冠状动脉疾病,心血管疾病的预后可能通过GGT水平升高来预测。GGT水平与慢性心力衰竭的心血管急症有关,GGT水平升高已被证明是心脏死亡和心脏移植的独立预测指标。研究GGT在心脏病机制中的作用将有助于制定预防策略和治疗方法。