Artem'eva N N, Sitkevich R V, Chalenko V V, Zlatin G S, Chalenko I O
Vestn Khir Im I I Grek. 1986 Aug;137(8):31-7.
A clinico-experimental investigation of the state of the coagulating, fibrinolytic and Kallikrein-Kinin systems of blood in the mechanical jaundice syndrome and different methods of its operative treatment has shown activation of these systems. In jaundice resulting from tumor of the pancreas head and Vater papilla activation of the coagulating system was prevailing while activation of the fibrinolytic and Kallikrein-Kinin systems prevailed in non-tumorous jaundice. The operative treatment aimed at the recovery of choledynamics resulted in normalization of the coagulating, fibrinolytic and Kallikrein-Kinin systems. Continuous bile loss through an external biliary fistula leads to their progressive suppression.
对机械性黄疸综合征患者血液的凝血、纤溶和激肽释放酶 - 激肽系统状态以及不同手术治疗方法进行的临床实验研究表明，这些系统被激活。在由胰头肿瘤和 Vater 乳头肿瘤引起的黄疸中，凝血系统的激活占主导，而在非肿瘤性黄疸中，纤溶和激肽释放酶 - 激肽系统的激活占主导。旨在恢复胆道动力学的手术治疗使凝血、纤溶和激肽释放酶 - 激肽系统恢复正常。通过外部胆瘘持续胆汁流失会导致这些系统逐渐受到抑制。
