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[来自母体和胎儿血液的绒毛间隙血栓的组成]

[Composition of intervillous thrombi from maternal and fetal blood].

作者信息

Gille J, Schwerd W, von Criegern T

出版信息

Z Geburtshilfe Perinatol. 1986 May-Jun;190(3):133-6.

PMID:2429464
Abstract

In serological studies blood groups of intervillous thrombi of the placenta were identical with maternal blood groups in 88.9%. Identity with fetal blood groups occurred in 11.1%. Utilizing an elution technique in smears prepared from intervillous thrombi, 11.68% of the erythrocytes were of fetal, 88.32% of maternal origin. In conclusion, intervillous thrombi are mainly composed of maternal cells. The existence of small amounts of fetal cells simultaneously, points to the possible etiology: Local damage of the trophoblastic epithelium of the villi is followed by escape of fetal cells into the intervillous space and later aggregation of maternal blood. Finally, the clinical relevance of intervillous thrombosis in maternal Rh-isoimmunization, pregnancy induced hypertension and intrauterine fetal anaemia is discussed.

摘要

在血清学研究中,胎盘绒毛间隙血栓的血型与母体血型相同的占88.9%。与胎儿血型相同的占11.1%。利用从绒毛间隙血栓制备的涂片的洗脱技术,11.68%的红细胞来自胎儿,88.32%来自母体。总之,绒毛间隙血栓主要由母体细胞组成。同时存在少量胎儿细胞这一点提示了可能的病因:绒毛滋养层上皮局部受损后,胎儿细胞逸入绒毛间隙,随后母体血液聚集。最后,讨论了绒毛间隙血栓形成在母体Rh血型免疫、妊娠高血压综合征和胎儿宫内贫血中的临床意义。

相似文献

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THE INCIDENCE AND SIGNIFICANCE OF INTERVILLOUS THROMBI IN THE HUMAN PLACENTA.人胎盘绒毛间血栓的发生率及意义
J Obstet Gynaecol Br Commonw. 1964 Dec;71:894-8. doi: 10.1111/j.1471-0528.1964.tb04376.x.

引用本文的文献

1
Maternal vs Fetal Origin of Placental Intervillous Thrombi.胎盘绒毛间血栓的母胎来源。
Am J Clin Pathol. 2022 Mar 3;157(3):365-373. doi: 10.1093/ajcp/aqab139.

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