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心脏手术后的成人呼吸窘迫综合征

Adult respiratory distress syndrome following cardiac surgery.

作者信息

Kogan A, Preisman S, Levin S, Raanani E, Sternik L

机构信息

Department of Cardiac Surgery, Sheba Medical Center, Tel Hashomer, Israel; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

J Card Surg. 2014 Jan;29(1):41-6. doi: 10.1111/jocs.12264. Epub 2013 Dec 3.

Abstract

BACKGROUND

Severe lung injury with the development of acute respiratory distress syndrome (ARDS) is a serious complication of cardiac surgery. The aim of this study was to determine the incidence, risk factors, and mortality of ARDS following cardiac surgery.

METHODS

We retrospectively analyze data in the period between January 2005 and March 2013.

RESULTS

Of 6069 patients who underwent cardiac surgery during the study period, 37 patients developed ARDS during the postoperative period. The incidence of ARDS was 0.61%, with a mortality of 40.5% (15 patients). Multivariate regression analysis identified previous cardiac surgery, complex cardiac surgery, and more than three transfusions with packed red blood cells (PRBC) were independent predictors for developing ARDS.

CONCLUSIONS

ARDS remains a serious, but very rare complication associated with significant mortality. In our study, previous cardiac surgery, complex cardiac surgery, and more than three transfusions of PRBC were independent predictors for the development of ARDS.

摘要

背景

严重肺损伤伴急性呼吸窘迫综合征(ARDS)的发生是心脏手术的一种严重并发症。本研究的目的是确定心脏手术后ARDS的发生率、危险因素及死亡率。

方法

我们回顾性分析了2005年1月至2013年3月期间的数据。

结果

在研究期间接受心脏手术的6069例患者中,37例在术后发生了ARDS。ARDS的发生率为0.61%,死亡率为40.5%(15例患者)。多因素回归分析确定,既往心脏手术、复杂心脏手术以及超过3次输注浓缩红细胞(PRBC)是发生ARDS的独立预测因素。

结论

ARDS仍然是一种严重但非常罕见的并发症,伴有显著的死亡率。在我们的研究中,既往心脏手术、复杂心脏手术以及超过3次输注PRBC是ARDS发生的独立预测因素。

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