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[卡氏肺孢子虫肺炎——综述]

[Pneumocystis carinii pneumonia--a review].

作者信息

Ziefer A, Jacobs T, Seitz H M

出版信息

Immun Infekt. 1986 Sep;14(5):170-7.

PMID:2429914
Abstract

Pneumocystis carinii pneumonia is a clinically, roentgenologically, and serologically uncharacteristic pneumonia of the immunodeficient patient and is caused by the opportunistic parasite Pneumocystis which is most likely a protozoon. The untreated disease is lethal. The epidemiologic, clinic, and histologic features of P. carinii pneumonia are different from those of the interstitial plasmacellular pneumonia that occurred in malnourished and premature infants between 1930 and 1960 in Europe and was caused by the same organism. P. carinii is restricted to the alveoli of the lung. Material for the direct microscopic diagnosis of the parasite can be produced by bronchoalveolar lavage. The trophozoites of P. carinii are preferably stained by Giemsa stain and the cystwalls by methenamine-silver. For a reliable diagnosis both methods should be used.

摘要

卡氏肺孢子虫肺炎是免疫缺陷患者临床上、放射学上和血清学上无特征性的肺炎,由机会性寄生虫卡氏肺孢子虫引起,该寄生虫很可能是一种原生动物。未经治疗的这种疾病是致命的。卡氏肺孢子虫肺炎的流行病学、临床和组织学特征与1930年至1960年间在欧洲营养不良和早产婴儿中发生的间质性浆细胞性肺炎不同,后者由相同病原体引起。卡氏肺孢子虫局限于肺的肺泡。可通过支气管肺泡灌洗获取用于直接显微镜诊断该寄生虫的材料。卡氏肺孢子虫的滋养体最好用吉姆萨染色,包囊壁用亚甲胺银染色。为了做出可靠的诊断,两种方法都应使用。

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