Azimova Komola, Rude Jennifer, Mallawaarachchi Indika, Dwivedi Alok, Sarosiek Jerzy, Mukherjee Debabrata
Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, TX, USA.
Division of Biostatistics & Epidemiology, Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, TX, USA.
Angiology. 2015 Jan;66(1):57-64. doi: 10.1177/0003319713513318. Epub 2013 Dec 3.
Depression is frequently associated with diabetes mellitus (DM) and may worsen DM-related morbidity and mortality. We determined the potential association of glucose levels with depression in Hispanic patients admitted to the Cardiovascular Intensive Care Unit. Patients were given the Center for Epidemiologic Studies-Depression scale survey within 24 hours of admission. Glycated hemoglobin and fasting blood glucose levels within 30 days of admission were extracted. The HbA1c levels remained significantly associated with both presence of depression and depression levels. Histories of DM, myocardial infarction, and percutaneous coronary intervention as well as baseline brain natriuretic peptide levels were also significantly associated with depression levels. The presence of a significant association between glucose levels and depression in Hispanic patients indicates that there is a need for optimal management of glycemic levels. This may then lead to better health outcomes in Hispanics with cardiovascular disease.
抑郁症常与糖尿病(DM)相关联,且可能会加重与糖尿病相关的发病率和死亡率。我们确定了入住心血管重症监护病房的西班牙裔患者血糖水平与抑郁症之间的潜在关联。患者在入院后24小时内接受了流行病学研究中心抑郁量表调查。提取了入院后30天内的糖化血红蛋白和空腹血糖水平。糖化血红蛋白水平与抑郁症的存在及抑郁程度均显著相关。糖尿病史、心肌梗死史、经皮冠状动脉介入治疗史以及基线脑钠肽水平也与抑郁程度显著相关。西班牙裔患者血糖水平与抑郁症之间存在显著关联,这表明需要对血糖水平进行优化管理。这进而可能会改善患有心血管疾病的西班牙裔患者的健康结局。