Gross Raz, Olfson Mark, Gameroff Marc J, Carasquillo Olveen, Shea Steven, Feder Adriana, Lantigua Rafael, Fuentes Milton, Weissman Myrna M
Division of Clinical and Genetic Epidemiology, New York State Psychiatric Institute, New York, NY, USA.
J Gen Intern Med. 2005 May;20(5):460-6. doi: 10.1111/j.1525-1497.2005.30003.x.
Maintaining optimal glycemic control is an important goal of therapy in patients with diabetes mellitus. Patients of Hispanic ancestry have been shown to have high rates of diabetes and poor glycemic control (PGC). Although depression is common in adults with diabetes, its relationship to glycemic control remains unclear, especially among Hispanics.
To assess the association of depression with PGC in Hispanics.
Data from a cross-sectional mental health survey in primary care were crosslinked to the hospital's computerized laboratory database.
Urban general medicine practice at a teaching hospital.
Two hundred and nine patients (mean [standard deviation] age, 57.1 [10.3] years; 68% females) with recent International Classification of Diseases, Ninth Revision (ICD-9) codes for diabetes mellitus, and 1 or more hemoglobin A(1c) (HbA(1c)) tests.
Probability of PGC (HbA(1c)>or=8%).
Probability for PGC steadily increased with severity of depression. Thirty-nine (55.7%) of the 70 patients with major depression had HbA(1c)>or=8%, compared with 39/92 (42.4%) in the minimal to mild depression group, and 15/47 (31.9%) in the no depression group (P(trend)=.01; adjusted odds ratio, 3.27; 95% confidence interval, 1.23 to 8.64, for moderate or severe depression vs no depression). Only 29 (41.4%) of the patients with major depression received mental health treatment in the previous year.
In this primary care sample of Hispanic patients with diabetes, we found a significant association between increasing depression severity and PGC. Yet, less than one half of the patients with moderate or severe depression received mental health treatment in the previous year. Improving identification and treatment of depression in this high-risk population might have favorable effects on diabetic outcomes.
维持最佳血糖控制是糖尿病患者治疗的一个重要目标。有研究表明,西班牙裔患者的糖尿病发病率高且血糖控制不佳(PGC)。虽然抑郁症在成年糖尿病患者中很常见,但其与血糖控制的关系仍不明确,尤其是在西班牙裔人群中。
评估西班牙裔人群中抑郁症与PGC之间的关联。
来自初级保健机构横断面心理健康调查的数据与医院的计算机化实验室数据库进行了交叉链接。
一家教学医院的城市普通内科诊所。
209例患者(平均[标准差]年龄为57.1[10.3]岁;68%为女性),近期有国际疾病分类第九版(ICD - 9)糖尿病编码,且进行过1次或多次糖化血红蛋白(HbA1c)检测。
PGC(HbA1c≥8%)的概率。
PGC的概率随抑郁症严重程度的增加而稳步上升。70例重度抑郁症患者中有39例(55.7%)HbA1c≥8%,而轻度至中度抑郁症组为39/92例(42.4%),无抑郁症组为15/47例(31.9%)(P趋势 = 0.01;中度或重度抑郁症与无抑郁症相比,调整后的优势比为3.27;95%置信区间为1.23至8.64)。在重度抑郁症患者中,只有29例(41.4%)在过去一年接受过心理健康治疗。
在这个西班牙裔糖尿病患者的初级保健样本中,我们发现抑郁症严重程度增加与PGC之间存在显著关联。然而,在过去一年中,中度或重度抑郁症患者中接受心理健康治疗的不到一半。改善这一高危人群中抑郁症的识别和治疗可能会对糖尿病治疗结果产生有利影响。