Hasan S S, Kushwaha A K
Pol J Pharmacol Pharm. 1986 Jul-Aug;38(4):329-34.
The effect of Datura alba (seed) extract on the brain and urinary metabolites of rats was studied. Treatment with Datura brought about a decrease in the activity of brain lipid peroxidase and catalase while an increase in the activity of fructose diphosphate aldolase and glucose 6-phosphate dehydrogenase was observed. An increase in the DNA and RNA contents of brain was noted after the treatment with Datura. The study also showed a marked decrease in the excretion of 5-hydroxyindole acetic acid and vanillyl mandelic acid in the urine of rats given Datura extract.
研究了白花曼陀罗（种子）提取物对大鼠脑和尿代谢产物的影响。用曼陀罗处理后，脑脂质过氧化物酶和过氧化氢酶的活性降低，而果糖二磷酸醛缩酶和葡萄糖6-磷酸脱氢酶的活性增加。用曼陀罗处理后，脑内DNA和RNA含量增加。该研究还表明，给予曼陀罗提取物的大鼠尿液中5-羟吲哚乙酸和香草扁桃酸的排泄量显著降低。
