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Extracorporeal Life Support Organization Registry Report 2012.体外生命支持组织登记报告 2012.
ASAIO J. 2013 May-Jun;59(3):202-10. doi: 10.1097/MAT.0b013e3182904a52.
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Effect of tidal volume, intrathoracic pressure, and cardiac contractility on variations in pulse pressure, stroke volume, and intrathoracic blood volume.潮气量、胸腔内压和心肌收缩力对脉搏压、每搏量和胸腔内血容量变化的影响。
Intensive Care Med. 2011 Oct;37(10):1672-9. doi: 10.1007/s00134-011-2304-3. Epub 2011 Jul 8.
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Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial.常规通气支持与体外膜肺氧合治疗成人严重呼吸衰竭的疗效及经济学评估(CESAR):一项多中心随机对照试验
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Update on safety equipment for extracorporeal life support (ECLS) circuits.体外生命支持(ECLS)回路安全设备的最新进展。
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Ability of pulse power, esophageal Doppler, and arterial pulse pressure to estimate rapid changes in stroke volume in humans.脉冲功率、食管多普勒及动脉脉压评估人体每搏量快速变化的能力。
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Cerebral tissue oxygen saturation during percutaneous cardiopulmonary support in a canine model of respiratory failure.
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Regional blood flow distribution from the proximal arterial cannula during veno-arterial extracorporeal membrane oxygenation in neonatal dog.新生犬静脉-动脉体外膜肺氧合期间近端动脉插管的局部血流分布
J Vet Med Sci. 1999 Apr;61(4):311-5. doi: 10.1292/jvms.61.311.
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Coronary arterial perfusion during venoarterial extracorporeal membrane oxygenation.静脉-动脉体外膜肺氧合期间的冠状动脉灌注
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The effect of extracorporeal membrane oxygenation on coronary perfusion and regional blood flow distribution.体外膜肺氧合对冠状动脉灌注及局部血流分布的影响。
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静脉-动脉体外膜肺氧合期间的区域灌注:一例病例报告及关于双循环概念的教学模块

Regional perfusion during venoarterial extracorporeal membrane oxygenation: a case report and educational modules on the concept of dual circulations.

作者信息

Alwardt Cory M, Patel Bhavesh M, Lowell Amelia, Dobberpuhl Jeff, Riley Jeffrey B, DeValeria Patrick A

机构信息

Mayo Clinic Hospital, Phoenix, Arizona 85054, USA.

出版信息

J Extra Corpor Technol. 2013 Sep;45(3):187-94.

PMID:24303602
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4557539/
Abstract

UNLABELLED

A challenging aspect of managing patients on venoarterial extracorporeal membrane oxygenation (V-A ECMO) is a thorough understanding of the relationship between oxygenated blood from the ECMO circuit and blood being pumped from the patient's native heart. We present an adult V-A ECMO case report, which illustrates a unique encounter with the concept of "dual circulations." Despite blood gases from the ECMO arterial line showing respiratory acidosis, this patient with cardiogenic shock demonstrated regional respiratory alkalosis when blood was sampled from the right radial arterial line. In response, a sample was obtained from the left radial arterial line, which mimicked the ECMO arterial blood but was dramatically different from the blood sampled from the right radial arterial line. A retrospective analysis of patient data revealed that the mismatch of blood gas values in this patient corresponded to an increased pulse pressure. Having three arterial blood sampling sites and data on the patient's pulse pressure provided a dynamic view of blood mixing and guided proper management, which contributed to a successful patient outcome that otherwise may not have occurred. As a result of this unique encounter, we created and distributed graphics representing the concept of "dual circulations" to facilitate the education of ECMO specialists at our institution.

KEYWORDS

ECMO, education, cardiopulmonary bypass, cannulation.

摘要

未标注

对接受静脉-动脉体外膜肺氧合(V-A ECMO)治疗的患者进行管理时,一个具有挑战性的方面是要透彻理解体外膜肺氧合回路中的氧合血与患者自身心脏泵出的血液之间的关系。我们报告一例成人V-A ECMO病例,该病例展示了与“双循环”概念的一次独特相遇。尽管体外膜肺氧合动脉管路中的血气显示为呼吸性酸中毒,但这位心源性休克患者在从右桡动脉采血时却表现出局部呼吸性碱中毒。作为回应,从左桡动脉采集了一份血样,其与体外膜肺氧合动脉血相似,但与从右桡动脉采集的血样有显著差异。对患者数据的回顾性分析显示,该患者血气值的不匹配与脉压升高相对应。拥有三个动脉采血部位以及患者脉压数据,提供了血液混合的动态视图并指导了正确的管理,这促成了原本可能不会出现的成功治疗结果。由于这次独特的经历,我们创建并分发了代表“双循环”概念的图表,以促进对我们机构体外膜肺氧合专家的培训。

关键词

体外膜肺氧合;培训;心肺转流;插管