Didier A, Benzarti M, Alazia M, Hémon Y, Senft M, Charpin J, Vervloët D
Ann Fr Anesth Reanim. 1986;5(4):361-6. doi: 10.1016/s0750-7658(86)80005-3.
A study was carried out on 36 patients who had presented with an anaphylactic reaction when they had been received anaesthetic induction agents including suxamethonium. After having been examined, they were assessed with various immunoallergic tests (skin tests, LHL, a search for specific anticholine IgE antibodies). They were compared with a group of 120 control patients with the same age, sex and professional characteristics. This study confirmed the part played by specific IgE antibodies in accidents involving suxamethonium. The specificity of the tests that could be used for the diagnosis was excellent. However, as far as sensitivity of the tests went, skin tests and LHL were more sensitive than the search for specific IgE antibodies. There was no statistical relationship between the limit for skin reactions and the degree of histamine release of the level of anticholine IgE antibody.
对36例在接受包括琥珀胆碱在内的麻醉诱导剂时出现过敏反应的患者进行了一项研究。在对他们进行检查后，用各种免疫过敏试验（皮肤试验、淋巴细胞组胺释放试验、寻找特异性抗胆碱能IgE抗体）对他们进行评估。将他们与一组年龄、性别和职业特征相同的120例对照患者进行比较。这项研究证实了特异性IgE抗体在涉及琥珀胆碱的意外事件中所起的作用。可用于诊断的试验的特异性极佳。然而，就试验的敏感性而言，皮肤试验和淋巴细胞组胺释放试验比寻找特异性IgE抗体更敏感。皮肤反应的界限与抗胆碱能IgE抗体水平的组胺释放程度之间没有统计学关系。
