Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Korean J Intern Med. 2013 Nov;28(6):724-7. doi: 10.3904/kjim.2013.28.6.724. Epub 2013 Oct 29.
Both Graves disease and Guillain-Barre syndrome (GBS) are autoimmune disorders caused by impaired self-tolerance mechanisms and triggered by interactions between genetic and environmental factors. GBS in patients who suffer from other autoimmune diseases is rarely reported, and the development of postinfectious GBS in a patient with Graves disease has not been previously reported in the literature. Herein, we report a patient with Graves disease who developed postinfectious GBS during a course of methimazole-induced agranulocytosis.
格雷夫斯病和吉兰-巴雷综合征(GBS)都是由自身耐受机制受损引起的自身免疫性疾病,由遗传和环境因素相互作用触发。在患有其他自身免疫性疾病的患者中,GBS 很少见,并且在文献中也没有报道过格雷夫斯病患者发生感染后 GBS。在此,我们报告了一例在使用甲巯咪唑诱导粒细胞缺乏症的过程中发生感染后 GBS 的格雷夫斯病患者。