Oshtrakh M I, Semionkin V A
FEBS Lett. 1986 Nov 24;208(2):331-6. doi: 10.1016/0014-5793(86)81044-4.
Human normal, adult and foetal oxyhaemoglobins and oxyhaemoglobins from leukaemic patients were studied, by Mössbauer spectroscopy. The estimations of quadrupole splitting delta EQ and isomer shift delta allow one to distinguish between adult, foetal and leukaemic oxyhaemoglobins. The differences in the Fe2+ electronic structure and active site molecular structure of foetal and leukaemic oxyhaemoglobins were analyzed.
通过穆斯堡尔光谱法研究了人类正常、成人和胎儿的氧合血红蛋白以及白血病患者的氧合血红蛋白。四极分裂δEQ和同质异能位移δ的估计值能够区分成人、胎儿和白血病患者的氧合血红蛋白。分析了胎儿和白血病患者氧合血红蛋白中Fe2+电子结构和活性部位分子结构的差异。
