Lebris A, Vildé A, Marret H, Body G, Ouldamer L
Département de gynécologie, hôpital Bretonneau, centre hospitalier régional universitaire de Tours, 2b, boulevard Tonnelé, 37044 Tours, France; Faculté de médecine François-Rabelais, 37044 Tours, France.
Département de radiologie, hôpital Bretonneau, centre hospitalier régional universitaire de Tours, 2b, boulevard Tonnelé, 37044 Tours, France.
Gynecol Obstet Fertil. 2014 Jan;42(1):14-9. doi: 10.1016/j.gyobfe.2013.08.004. Epub 2013 Dec 3.
To investigate the role of imaging procedures in the diagnosis of synchronous bilateral breast cancer (SBBC) PATIENTS AND METHODS: The patient group consisted of consecutive women undergoing managed for SBBC in our institution between January 2006 and July 2012. We defined SBBC as bilateral breast tumors diagnosed simultaneously or up to 3 months after initial diagnosis. Clinical data included comorbidities, BMI (kg/m(2)), preoperative breast imaging modalities used and their findings.
Of the 2322 patients with newly diagnosed breast cancer treated on the study period, 46 patients with the diagnosis of SBBC were enrolled to the study. A total of 41.3% patients had family history of breast cancer. A total of 56.52% had clinical symptoms. The most frequent situation of diagnosis (32.6%) was the association of a palpable tumor and a contralateral radiologic abnormality. MRI permitted the diagnosis of 19.6% occult contralateral lesions.
Clinical examination and conventional imaging procedures (mammography and sonography) detects the majority (76%) of synchronous contralateral breast cancers. A family history of breast cancer, a multifocal breast tumor or the presence of an invasive lobular carcinoma should be arguments for the realization of a breat MRI to eliminate contralateral malignancy.
探讨影像学检查在同步性双侧乳腺癌(SBBC)诊断中的作用。
患者组包括2006年1月至2012年7月期间在我院接受SBBC治疗的连续女性患者。我们将SBBC定义为同时诊断或在初次诊断后3个月内诊断出的双侧乳腺肿瘤。临床数据包括合并症、体重指数(kg/m²)、术前使用的乳腺成像方式及其结果。
在研究期间接受新诊断乳腺癌治疗的2322例患者中,46例诊断为SBBC的患者被纳入研究。共有41.3%的患者有乳腺癌家族史。共有56.52%的患者有临床症状。最常见的诊断情况(32.6%)是可触及肿瘤与对侧影像学异常同时存在。MRI能够诊断出19.6%的隐匿性对侧病变。
临床检查和传统影像学检查(乳腺X线摄影和超声检查)可检测出大多数(76%)的同步性对侧乳腺癌。乳腺癌家族史、多灶性乳腺肿瘤或浸润性小叶癌的存在应作为进行乳腺MRI检查以排除对侧恶性肿瘤的依据。