T.H. Morgan School of Biological Sciences and the Graduate Center for Toxicology, University of Kentucky, 40506, Lexington, Kentucky.
J Chem Ecol. 1985 Apr;11(4):539-44. doi: 10.1007/BF00989564.
The seed predator,Caryedes brasiliensis [Bruchidae] generates appreciable ammonia in its dietary use and detoxification ofL-canavanine and its catabolic product,L-canaline.L-Canavanine is a toxic allelochemical ofDioclea megacarpa seeds, the food of the developing larvae. Bruchid beetle larvae rely upon glutamic acid dehydrogenase and glutamine synthetase to use ammonia for glutamic acid synthesis from 2-oxoglutaric acid and conversion of the former to glutamine. These reactions provide the larvae with a means for metabolically eliminating ammonia. Proline serves as a carbon skeleton source for glutamic acid formation.
种子捕食者巴西豆象（Bruchidae）在食用和解毒 L-刀豆氨酸及其代谢产物 L-瓜氨酸时会产生可观的氨。L-刀豆氨酸是大果野百合种子中的一种有毒化感物质，也是发育中幼虫的食物。象甲幼虫依靠谷氨酸脱氢酶和谷氨酰胺合成酶利用氨，从 2-氧戊二酸合成谷氨酸，并将前者转化为谷氨酰胺。这些反应为幼虫提供了一种代谢消除氨的方法。脯氨酸可作为谷氨酸形成的碳骨架来源。
