Snir M, Dotan A, Friling R, Ron-Kella Y, Goldenberg-Cohen N, Stiebel-Kalish H
1] Pediatric Ophthalmology Unit, Schneider Children's Medical Center of Israel, Petach Tikva, Israel [2] Department of Ophthalmology, Rabin Medical Center, Petach Tikva, Israel [3] Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Department of Ophthalmology, Rabin Medical Center, Petach Tikva, Israel.
Eye (Lond). 2014 Mar;28(3):279-84. doi: 10.1038/eye.2013.260. Epub 2013 Dec 6.
The aim of this study was to evaluate the motor, sensory, functional, and head posture results of recession of the lateral rectus muscle contralateral to the involved eye in patients with exotropic Duane retraction syndrome (DRS) type 3.
This was a retrospective, longitudinal, observational study of a consecutive clinical case series. Of the 11 patients with DRS type 3 operated on at a tertiary medical center from 1977 to 2012, 8 underwent recession of the lateral rectus muscle contralateral to the involved eye (with combined Y-splitting of ipsilateral lateral rectus muscle in 3 of them). Full ophthalmic, orthoptic, and neurological examination was performed before and after surgery. Main outcome measures included intragroup changes in motor misalignment, abnormal head turn, ocular upshoot, and stereopsis.
Mean patient age was 8.75±3.1 years at surgery. Mean exodeviation for distance was -17.3±3.5 prism diopters (PD) preoperatively and -4.0±6.1 PD postoperatively; corresponding values for near were -23.1±7.2 PD and -5.9±8.7 PD. Motor deviation improved by 77% for distance (P=0.017) and 74.5% for near (P=0.01). In 7/8 patients, the postoperative residual exodeviation (distance and near) was <8.0 PD. There was an 80% improvement in head turn, from 15.3±4° before surgery to 3.1±5.0° after (P=0.01). Stereopsis improved significantly in 6/8 patients. Findings remained stable during follow-up (mean duration 35.9±50.8 months, range 5-132 months).
Contralateral lateral rectus muscle recession appears to be a promising technique for the treatment of moderate unilateral DRS type 3, with patients showing significant motor and functional improvement and a decrease in head turn.
本研究旨在评估外斜视型杜安眼球后退综合征(DRS)3型患者患眼对侧外直肌后徙术后的运动、感觉、功能及头部姿势结果。
这是一项对连续临床病例系列的回顾性、纵向观察性研究。在1977年至2012年于一家三级医疗中心接受手术的11例3型DRS患者中,8例接受了患眼对侧外直肌后徙术(其中3例同时行同侧外直肌Y形劈开术)。在手术前后进行了全面的眼科、视光学及神经学检查。主要观察指标包括组内运动性斜视、异常头位转动、眼球上转及立体视的变化。
手术时患者平均年龄为8.75±3.1岁。远距离平均外斜视术前为-17.3±3.5棱镜度(PD),术后为-4.0±6.1 PD;近距离相应值术前为-23.1±7.2 PD,术后为-5.9±8.7 PD。远距离运动性斜视改善了77%(P=0.017),近距离改善了74.5%(P=0.01)。8例患者中有7例术后远距离和近距离的残余外斜视<8.0 PD。头位转动改善了80%,从术前的15.3±4°降至术后的3.1±5.0°(P=0.01)。8例患者中有6例立体视显著改善。随访期间结果保持稳定(平均时长35.9±50.8个月,范围5 - 132个月)。
对侧外直肌后徙术似乎是治疗中度单侧3型DRS的一种有前景的技术,患者的运动和功能有显著改善,头位转动减少。