Zhang Yan, Gao Hua, Gao Wei
Department of Nursing, Qilu Hospital, Shandong University, West Wenhua Xi Road No. 107, Jinan, 250012, People's Republic of China,
Tumour Biol. 2014 Apr;35(4):3563-8. doi: 10.1007/s13277-013-1470-z. Epub 2013 Dec 6.
Drain insertion is routinely done after breast cancer surgery. However, the prognostic value of suction drains in breast cancer is still unknown. This study aimed to reveal the prognostic value of drain insertion in breast cancer. A total of 296 female breast cancer patients undergoing surgery were retrospectively recruited. The correlation of drainage volume as well as drain duration with clinicopathological parameters and prognosis was assessed statistically. We found that breast cancer patients with a drainage volume of >240 ml had a better overall survival time. Breast cancer patients with more than 5 days postoperative drain duration would have better survival time. In addition, both the volume and duration of wound drainage are independent prognostic factors in multivariate analysis. Therefore, the volume of drainage as well as drain duration is a potential novel prognostic marker for breast cancer.
乳腺癌手术后常规会进行引流管插入。然而，乳腺癌中负压引流管的预后价值仍不明确。本研究旨在揭示乳腺癌引流管插入的预后价值。共回顾性纳入了296例接受手术的女性乳腺癌患者。对引流量、引流持续时间与临床病理参数及预后的相关性进行了统计学评估。我们发现，引流量>240 ml的乳腺癌患者总生存时间更好。术后引流持续时间超过5天的乳腺癌患者生存时间更佳。此外，在多因素分析中，伤口引流量和持续时间均为独立的预后因素。因此，引流量和引流持续时间是乳腺癌潜在的新型预后标志物。
