Laboratoire de Biologie et Génétique Evolutives du CNRS, 91190, Gif-sur-Yvette, France.
J Chem Ecol. 1985 Dec;11(12):1617-29. doi: 10.1007/BF01012116.
Cuticular aphrodisiacs fromD. melanogaster females were further characterized and the male response specificity towards such natural and synthetic unsaturated hydrocarbons was investigated. The behavioral activity seems to be correlated with some chain-length requirement and double-bond position; at least one double bond in position 7 seems necessary. This position is more abundant among natural monoenes, and among dienes which also bear a second double bond in position 11, whatever the chain length. Bioassays of the synthetic (Z,Z)-7,11-heptacosadiene yielded a dose-response curve close to that of the natural mixture of heptacosadienes in which the 7-11 isomer is predominant. This female specific 7,11 heptacosadiene appears to be the most potent aphrodisiac for males of the species. Its threshold is lower than that of both 7,11-nonacosadiene and 7-pentacosene which might also play a role in sex and species recognition.
黑腹果蝇雌蝇的表皮性外激素进一步被定性，同时研究了雄蝇对这些天然和合成不饱和碳氢化合物的特殊反应。这种行为活性似乎与某些链长要求和双键位置有关；在位置 7 中至少有一个双键似乎是必要的。在天然单烯中，这个位置更为丰富，而在二烯中，无论链长如何，在位置 11 也有第二个双键。对合成 (Z,Z)-7,11-二十七碳二烯的生物测定得到的剂量反应曲线接近于天然二十七碳二烯混合物的曲线，其中 7-11 异构体占优势。这种雌性特异性的 7,11 二十七碳二烯似乎是该物种雄蝇最有效的性外激素。它的阈值低于 7,11-二十九碳二烯和 7-二十五碳烯，这两种物质也可能在性和种间识别中发挥作用。
