Munshi Vidit, McMahon Pamela
Institute for Technology Assessment, Massachusetts General Hospital, Boston, MA.
Curr Surg Rep. 2013 Dec;1(4). doi: 10.1007/s40137-013-0030-1.
Early detection of lung cancer and smoking cessation interventions can decrease lung cancer mortality, but information on the effectiveness and interaction between smoking cessation and lung cancer screening is sparse and inconsistent. This review aims to synthesize recent studies in two major areas of interest. First, we explore the interactions and potential for synergies between lung cancer screening programs and smoking cessation by summarizing reported changes in smoking behavior observed in major screening trials in the United States and Europe, as well as attempts to use smoking cessation interventions to augment the benefits from lung cancer screening programs. Second, we review the interaction between smoking habits and pre/post-operative pulmonary resection outcomes, including changes in smoking behavior post-diagnosis and post-treatment. Information from these areas should allow us to maximize benefits from smoking cessation interventions through the entire lung cancer screening process, from the screen itself through potential curative resection after diagnosis.
肺癌的早期检测和戒烟干预措施可以降低肺癌死亡率，但关于戒烟与肺癌筛查之间的有效性及相互作用的信息却稀少且不一致。本综述旨在综合近期在两个主要关注领域的研究。首先，我们通过总结在美国和欧洲的主要筛查试验中观察到的吸烟行为的报告变化，以及利用戒烟干预措施来增强肺癌筛查项目益处的尝试，探讨肺癌筛查项目与戒烟之间的相互作用及协同增效的潜力。其次，我们回顾吸烟习惯与肺切除手术前后结果之间的相互作用，包括诊断后和治疗后的吸烟行为变化。这些领域的信息应能使我们在从筛查本身到诊断后潜在的根治性切除的整个肺癌筛查过程中，最大限度地从戒烟干预措施中获益。
